GABAergic synapses upon neurons expressing substance P receptors in the nucleus of the solitary tract: An immunocytochemical electron microscope study in the rat

被引:13
作者
Jia, HG [1 ]
Wang, BR [1 ]
Rao, ZR [1 ]
Shi, JW [1 ]
Shigemoto, R [1 ]
Kaneko, T [1 ]
Mizuno, N [1 ]
机构
[1] KYOTO UNIV,FAC MED,DEPT MORPHOL BRAIN SCI,KYOTO 60601,JAPAN
关键词
nucleus of the solitary tract; gamma-aminobutyric acid; substance P receptor; synapses; baroreflex; electron microscopy; immunohistochemistry; rat;
D O I
10.1016/0304-3940(96)12654-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Morphological substrates for interactions between gamma-aminobutyric acid (GABA) and substance P upon neurons expressing substance P receptor (SPR) in the nucleus of the solitary tract (NST) were investigated by immunocytochemical electron microscopy. In the NST of the rat, many GABA-like immunoreactive axon terminals were in symmetric synaptic contacts with dendritic profiles; they were observed on nearly a half of the SPR-like immunoreactive dendritic profiles in the medial part of the caudal half of the NST.
引用
收藏
页码:49 / 52
页数:4
相关论文
共 19 条
[1]   GLUTAMIC-ACID DECARBOXYLASE IMMUNOREACTIVITY IS PRESENT IN PERIKARYA OF NEURONS IN NUCLEUS TRACTUS SOLITARIUS OF RAT [J].
BLESSING, WW ;
OERTEL, WH ;
WILLOUGHBY, JO .
BRAIN RESEARCH, 1984, 322 (02) :346-350
[2]   SUBSTANCE-P MICROINJECTIONS INTO THE NUCLEUS TRACTUS SOLITARIUS ELICIT A PRESSOR-RESPONSE IN CAPSAICIN-TREATED RATS [J].
CARTER, DA ;
LIGHTMAN, SL .
NEUROSCIENCE LETTERS, 1983, 43 (2-3) :253-257
[3]   GABAERGIC MECHANISMS IN NUCLEUS TRACTUS SOLITARIUS ALTER BLOOD-PRESSURE AND VASOPRESSIN RELEASE [J].
CATELLI, JM ;
GIAKAS, WJ ;
SVED, AF .
BRAIN RESEARCH, 1987, 403 (02) :279-289
[4]   CARDIOVASCULAR EFFECTS OF SUBSTANCE-P PEPTIDES IN THE NUCLEUS OF THE SOLITARY TRACT [J].
HALL, ME ;
MILEY, FB ;
STEWART, JM .
BRAIN RESEARCH, 1989, 497 (02) :280-290
[5]   SUBSTANCE-P AS A BARORECEPTOR AND CHEMORECEPTOR AFFERENT NEUROTRANSMITTER - IMMUNO-CYTOCHEMICAL AND NEUROCHEMICAL EVIDENCE IN THE RAT [J].
HELKE, CJ ;
ODONOHUE, TL ;
JACOBOWITZ, DM .
PEPTIDES, 1980, 1 (01) :1-9
[6]   DEMONSTRATION OF SUBSTANCE-P IN AORTIC NERVE AFFERENT-FIBERS BY COMBINED USE OF FLUORESCENT RETROGRADE NEURONAL LABELING AND IMMUNOCYTOCHEMISTRY [J].
HELKE, CJ ;
GOLDMAN, W ;
JACOBOWITZ, DM .
PEPTIDES, 1980, 1 (04) :359-364
[7]   EFFECTS OF GLUTAMATE, SUBSTANCE-P AND ELEDOISIN-RELATED PEPTIDE ON SOLITARY TRACT NEURONS INVOLVED IN RESPIRATION AND RESPIRATORY REFLEXES [J].
HENRY, JL ;
SESSLE, BJ .
NEUROSCIENCE, 1985, 14 (03) :863-&
[8]   BRAIN-STEM PROJECTIONS OF THE GLOSSOPHARYNGEAL NERVE AND ITS CAROTID-SINUS BRANCH IN THE RAT [J].
HOUSLEY, GD ;
MARTINBODY, RL ;
DAWSON, NJ ;
SINCLAIR, JD .
NEUROSCIENCE, 1987, 22 (01) :237-250
[9]   USE OF AVIDIN-BIOTIN-PEROXIDASE COMPLEX (ABC) IN IMMUNOPEROXIDASE TECHNIQUES - A COMPARISON BETWEEN ABC AND UNLABELED ANTIBODY (PAP) PROCEDURES [J].
HSU, SM ;
RAINE, L ;
FANGER, H .
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1981, 29 (04) :577-580
[10]   BLOOD-PRESSURE MODULATION BY SUBSTANCE-P IN THE RAT NUCLEUS TRACTUS SOLITARIUS [J].
KUBO, T ;
KIHARA, M .
BRAIN RESEARCH, 1987, 413 (02) :379-383