Comparison of retinal nerve fiber layer thickness measurements by spectral-domain optical coherence tomography systems using a phantom eye model

被引：24

作者：

de Kinkelder, Roy ^{[1
,3
]}

de Bruin, Daniel M. ^{[1
]}

Verbraak, Frank D. ^{[1
,2
]}

van Leeuwen, Ton G. ^{[1
,4
,5
]}

Faber, Dirk J. ^{[1
,2
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Biomed Engn & Phys, NL-1100 DE Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Dept Ophthalmol, NL-1100 DE Amsterdam, Netherlands

[3] Topcon Europe Med Bv, NL-2908 LJ Capelle Aan Den Ijssel, Netherlands

[4] Univ Twente, MIRA Inst Biomed Technol & Tech Med, NL-7500 AE Enschede, Netherlands

[5] Univ Twente, Fac Sci & Technol, Biomed Photon Imaging Grp, NL-7500 AE Enschede, Netherlands

来源：

JOURNAL OF BIOPHOTONICS | 2013年 / 6卷 / 04期

关键词：

phantom eye model; optical coherence tomography; system calibration; nerve fiber layer thickness; OCT; REPRODUCIBILITY; TISSUE;

D O I：

10.1002/jbio.201200018

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

To quantify differences in nerve fiber layer thickness measurements by various spectral-domain optical coherence tomography (SD-OCT) systems, we developed a phantom eye model. We tested twelve SD-OCT systems of four manufacturers. All systems combined overestimated the 49 mu m thick phantom RNFL thickness on average by 18 mu m. Within brands, thickness measurements differed statistically significant for one Topcon, one RTVue and one Cirrus. Between brands, thickness determined with RTVue and Topcon differed statistically significant from Cirrus and Spectralis. The maximum difference between mean thicknesses is 3.6 mu m within brands and 7.7 mu m between brands. ((c) 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

引用

页码：314 / 320

页数：7

共 21 条

[21] Recent developments in optical coherence tomography for imaging the retina [J].

van Velthoven, Mirjam E. J. ;

Faber, Dirk J. ;

Verbraak, Frank D. ;

van Leeuwen, Ton G. ;

de Smet, Marc D. .

PROGRESS IN RETINAL AND EYE RESEARCH, 2007, 26 (01) :57-77

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