High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

被引:0
|
作者
Sparkenbaugh, Erica [1 ]
Wilson, Kathryn [2 ]
Kasztan, Malgorzata [3 ]
Pollock, David M. [3 ]
McCrae, Keith R. [4 ]
Pawlinski, Rafal [5 ]
机构
[1] Univ N Carolina, McAllister Heart Inst, Chapel Hill, NC USA
[2] Univ N Carolina, McAllister Heart Inst, Chapel Hill, NC 27515 USA
[3] Univ Alabama Birmingham, Dept Med, Div Nephrol, Birmingham, AL 35294 USA
[4] Cleveland Clin, Taussig Canc Inst, Dept Hematol & Med Oncol, Cleveland, OH 44106 USA
[5] Univ N Carolina, Div Hematol Oncol, Chapel Hill, NC 27515 USA
关键词
D O I
10.1182/blood-2018-99-116526
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
268
引用
收藏
页数:2
相关论文
共 40 条
  • [1] High molecular weight kininogen contributes to early mortality and kidney dysfunction in a mouse model of sickle cell disease
    Sparkenbaugh, Erica M.
    Kasztan, Malgorzata
    Henderson, Michael W.
    Ellsworth, Patrick
    Davis, Parker Ross
    Wilson, Kathryn J.
    Reeves, Brandi
    Key, Nigel S.
    Strickland, Sidney
    McCrae, Keith
    Pollock, David M.
    Pawlinski, Rafal
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020, 18 (09) : 2329 - 2340
  • [2] Hemoglobin and End-Organ Damage in Individuals with Sickle Cell Disease
    Ershler, William B.
    De Castro, Laura M.
    Pakbaz, Zahra
    Moynahan, Aaron
    Weycker, Derek
    Delea, Thomas E.
    Agodoa, Irene
    Cong, Ze
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 2023, 98
  • [3] Deficiency of High Molecular Weight Kininogen Attenuates Cardiovascular Complication in a Mouse Model of Sickle Cell Disease
    Sparkenbaugh, Erica M.
    Wilson, Kathryn J.
    Kasztan, Malgorzata
    Pollock, David
    McCrae, Keith
    Pawlinski, Rafal
    CIRCULATION, 2018, 138
  • [4] Ambulatory Hypertension in Pediatric Patients With Sickle Cell Disease and Its Association With End-Organ Damage
    Ranabothu, Saritha
    Hafeman, Michael
    Manwani, Deepa
    Reidy, Kimberly
    Morrone, Kerry
    Lorenzo, Josemiguel
    Tria, Barbara
    Kaskel, Frederick
    Mahgerefteh, Joseph
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (11)
  • [5] Clustering of end-organ disease and earlier mortality in adults with sickle cell disease: A retrospective-prospective cohort study
    Chaturvedi, Shruti
    Ghafuri, Djamila Labib
    Jordan, Natalie
    Kassim, Adetola
    Rodeghier, Mark
    DeBaun, Michael R.
    AMERICAN JOURNAL OF HEMATOLOGY, 2018, 93 (09) : 1153 - 1160
  • [6] EP1 Disruption Attenuates End-Organ Damage in a Mouse Model of Hypertension
    Bartlett, Christina S.
    Boyd, Kelli L.
    Harris, Raymond C.
    Zent, Roy
    Breyer, Richard M.
    HYPERTENSION, 2012, 60 (05) : 1184 - +
  • [7] Kininogen deficiency attenuates thrombin generation in a mouse model of sickle cell disease
    Sparkenbaugh, E.
    Key, N. S.
    Chandarajoti, K.
    Gruber, A.
    Mackman, N.
    McCrae, K.
    Pawlinski, R.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2015, 13 : 17 - 18
  • [8] Calpain-1 Contributes to Pain and Organ Damage in Sickle Cell Disease
    Kiven, Stacy B.
    Lei, Jianxun
    Sagi, Varun
    Huy Tran
    Wang, Ying
    Pagare, Piyusha P.
    Nwankwo, Jennifer O.
    Lambrecht, Nils
    Gupta, Kalpna
    BLOOD, 2019, 134
  • [9] The Impact of Hemoglobin Level on Risk of End-Organ Damage among Patients with Sickle Cell Disease - A Large-Scale, Longitudinal Analysis
    Ershler, William B.
    De Castro, Laura M.
    Pakbaz, Zahra
    Moynahan, Aaron
    Weycker, Derek
    Pham, Nhat
    Delea, Thomas E.
    Agodoa, Irene
    Cong, Ze
    BLOOD, 2020, 136
  • [10] Assessment of End-Organ Damage Among Elderly Patients with Sickle Cell Anemia: A Single-Center Retrospective Study
    Kannan, Preethi
    Soliman, Sara
    Dambala, Nehaa
    Idowu, Modupe
    BLOOD, 2024, 144 : 5343 - 5344