Geriatric nutritional risk index is associated with 30-day mortality in patients with acute respiratory distress syndrome

The clinical effect of the geriatric nutritional risk index (GNRI) on patients with acute respiratory distress syndrome (ARDS) remains unclear. The aim of this study was to evaluate the association between the GNRI on admission and 30-day mortality in patients with ARDS. From January 2014 to May 2019, we retrospectively reviewed medical records for patients with ARDS admitted to a medical intensive care unit, who met for the Berlin definition. The GNRI was calculated as follows: 1.519 x serum albumin, (g/L) + (41.7 x present weight, kg/ideal body weight, kg). Clinical data of 224 patients were analyzed. Median age was 72 years old and 71.4% was men. ARDS was mostly of pulmonary origin (94.2%). 30-day mortality was 61.6% (138/224). APACHE II and SOFA scores and the frequency of septic shock and acute kidney injury, were significantly higher in non-survivors. The median GNRI score was higher in survivors than in non-survivors (86.9 vs 79.8,P = .001). In multivariate analysis, GNRI scores were associated with 30-day mortality (hazard ratio, 0.978; 95% confidence interval 0.966-0.990,P = .001). The GNRI on admission was associated with 30-day mortality and may be useful index to assess mortality in patients with ARDS.