Fibrolamellar Hepatocellular Carcinoma: Treatment with Yttrium-90 and Subsequent Surgical Resection

被引：20

作者：

Mafeld, Sebastian ^{[1
]}

French, Jeremy ^{[2
]}

Tiniakos, Dina ^{[3
]}

Haugk, Beate ^{[4
]}

Manas, Derek ^{[2
]}

Littler, Peter ^{[1
]}

机构：

[1] Freeman Rd Hosp, Dept Intervent Radiol, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England

[2] Freeman Rd Hosp, Dept Hepatobiliary Surg, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England

[3] Newcastle Univ, Inst Cellular Med, Fac Med Sci, W Leech Bldg,M4-143,Framlington Pl, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

[4] Newcastle Upon Tyne Hosp NHS Fdn Trust, Dept Cellular Pathol, Royal Victoria Infirm, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England

来源：

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY | 2018年 / 41卷 / 05期

关键词：

Fibrolamellar hepatocellular carcinoma; Radioembolization; SIRT; TARE; Yttrium-90; Liver resection; LIVER RESECTION; RADIOEMBOLIZATION; THERAPY;

D O I：

10.1007/s00270-018-1903-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a 52-year-old female patient who presented with a 9.5-cm fibrolamellar hepatocellular carcinoma (FL-HCC). The patient was initially unsuitable for surgical resection and therefore underwent transarterial chemoembolization followed by selective internal radiation therapy (SIRT) with Yttrium-90 to downsize the tumour. Following SIRT, the tumour decreased in volume from 350 to 20 cm(3) allowing curative (R0) resection with an extended left hepatectomy and reconstruction of IVC. This is the first reported case of FL-HCC treated with SIRT in which, due to the good SIRT response, the patient was downsized to allow curative resection.

引用

页码：816 / 820

页数：5

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