GLP-1 Effects on Islets: Hormonal, Neuronal, or Paracrine?

被引：61
作者：
Donath, Marc Y. [1 ]
Burcelin, Remy [2 ]
机构：
[1] Univ Basel Hosp, Clin Endocrinol Diab & Metab, CH-4031 Basel, Switzerland
[2] Fac Med Toulouse, INSERM, Inst Malad Metabol & Cardiovasc, U1048, F-31073 Toulouse, France
来源：
DIABETES CARE | 2013年 / 36卷
关键词：
GLUCAGON-LIKE PEPTIDE-1; PANCREATIC ALPHA-CELLS; INSULIN-SECRETION; GASTRIC BYPASS; PC1/3; EXPRESSION; BETA-CELLS; PROGLUCAGON; ACTIVATION; RECEPTOR; SENSOR;
D O I：
10.2337/dcS13-2015
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：S145 / S148
页数：4
相关论文
共 40 条
  • [1] Brain activation following peripheral administration of the GLP-1 receptor agonist exendin-4
    Baraboi, Elena-Dana
    St-Pierre, David H.
    Shooner, Julie
    Timofeeva, Elena
    Richard, Denis
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2011, 301 (04) : R1011 - R1024
  • [2] HAMSTER PREPROGLUCAGON CONTAINS THE SEQUENCE OF GLUCAGON AND 2 RELATED PEPTIDES
    BELL, GI
    SANTERRE, RF
    MULLENBACH, GT
    [J]. NATURE, 1983, 302 (5910) : 716 - 718
  • [3] Unique Arrangement of α- and β-Cells in Human Islets of Langerhans
    Bosco, Domenico
    Armanet, Mathieu
    Morel, Philippe
    Niclauss, Nadja
    Sgroi, Antonino
    Muller, Yannick D.
    Giovannoni, Laurianne
    Parnaud, Geraldine
    Berney, Thierry
    [J]. DIABETES, 2010, 59 (05) : 1202 - 1210
  • [4] Portal glucose infusion in the mouse induces hypoglycemia - Evidence that the hepatoportal glucose sensor stimulates glucose utilization
    Burcelin, R
    Dolci, W
    Thorens, B
    [J]. DIABETES, 2000, 49 (10) : 1635 - 1642
  • [5] Glucose sensing by the hepatoportal sensor is GLUT2-dependent - In vivo analysis in GLUT2-null mice
    Burcelin, R
    Dolci, W
    Thorens, B
    [J]. DIABETES, 2000, 49 (10) : 1643 - 1648
  • [6] GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization
    Burcelin, R
    Crivelli, V
    Perrin, C
    Da Costa, A
    Mu, J
    Kahn, BB
    Birnbaum, MJ
    Kahn, CR
    Vollenweider, P
    Thorens, B
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (10) : 1555 - 1562
  • [7] Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
    Burcelin, R
    Da Costa, A
    Drucker, D
    Thorens, B
    [J]. DIABETES, 2001, 50 (08) : 1720 - 1728
  • [8] Cabou Cendrine, 2011, Rev Diabet Stud, V8, P418, DOI 10.1900/RDS.2011.8.418
  • [9] Circulation and degradation of GIP and GLP-1
    Deacon, CF
    [J]. HORMONE AND METABOLIC RESEARCH, 2004, 36 (11-12) : 761 - 765
  • [10] Type 2 diabetes as an inflammatory disease
    Donath, Marc Y.
    Shoelson, Steven E.
    [J]. NATURE REVIEWS IMMUNOLOGY, 2011, 11 (02) : 98 - 107
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