Application of several modified peak purity assays to real complex multicomponent mixtures by high-performance liquid chromatography with diode-array detection

被引：25

作者：

Frenich, AG ^{[1
]}

Torres-Lapasió, JR

De Braekeleer, K

Massart, DL

Vidal, JLM

Galera, MM

机构：

[1] Univ Almeria, Dept Hydrogeol & Analyt Chem, Almeria 04071, Spain

[2] Free Univ Brussels, ChemoAC, B-1090 Brussels, Belgium

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 855卷 / 02期

关键词：

needle search; orthogonal projection; SIMPLISMA; curve resolution; peak purity; chemometrics;

D O I：

10.1016/S0021-9673(99)00709-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Simple to use interactive self-modelling mixture analysis (SIMPLISMA), orthogonal projection (OPA) and Needle Search (NS) approaches have been applied to the determination of a number of compounds present in a complex multicomponent system. None of these three approaches succeeded completely when they were tested using the whole data matrix. When OPA and NS were applied to three simpler submatrices, obtained by dividing the total data matrix, and where a smaller number of compounds were present, better performance was achieved. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：487 / 499

页数：13

共 24 条

[1] ASSESSING CHROMATOGRAPHIC PEAK PURITY USING CONDITION INDEX AND SINGULAR-VALUE EVOLVING PROFILES
BAKKEN, GA
KALIVAS, JH
[J]. ANALYTICA CHIMICA ACTA, 1995, 300 (1-3) : 173 - 181
[2] CUESTA F, 1995, ANAL CHIM ACTA, V314, P131
[3] Evaluation of the orthogonal projection approach (OPA) and the SIMPLISMA approach on the Windig standard spectral data sets
De Braekeleer, K
Massart, DL
[J]. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 1997, 39 (02) : 127 - 141
[4] Influence and correction of temperature perturbations on NIR spectra during the monitoring of a polymorph conversion process prior to self-modelling mixture analysis
DeBraekeleer, K
Sanchez, FC
Hailey, PA
Sharp, DCA
Pettman, AJ
Massart, DL
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1998, 17 (01) : 141 - 152
[5] Application of the needle algorithm for exploratory analysis and resolution of HPLC-DAD data
deJuan, A
vandenBogaert, B
Sanchez, FC
Massart, DL
[J]. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 1996, 33 (02) : 133 - 145
[6] Application of eigenstructure tracking analysis and SIMPLISMA to the study of the protonation equilibria of cCMP and several polynucleotides
Gargallo, R
Sanchez, FC
IzquierdoRidorsa, A
Massart, DL
[J]. ANALYTICAL CHEMISTRY, 1996, 68 (13) : 2241 - 2247
[7] A PRIORI ESTIMATES OF THE ELUTION PROFILES OF THE PURE COMPONENTS IN OVERLAPPED LIQUID-CHROMATOGRAPHY PEAKS USING TARGET FACTOR-ANALYSIS
GEMPERLINE, PJ
[J]. JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 1984, 24 (04): : 206 - 212
[8] JARVIS TD, 1992, ANAL CHIM ACTA, V26, P13
[9] WINDOW EVOLVING FACTOR-ANALYSIS FOR ASSESSMENT OF PEAK HOMOGENEITY IN LIQUID-CHROMATOGRAPHY
KELLER, HR
MASSART, DL
DEBEER, JO
[J]. ANALYTICAL CHEMISTRY, 1993, 65 (04) : 471 - 475
[10] HEURISTIC EVOLVING LATENT PROJECTIONS - RESOLVING 2-WAY MULTICOMPONENT DATA .1. SELECTIVITY, LATENT-PROJECTIVE GRAPH, DATASCOPE, LOCAL RANK, AND UNIQUE RESOLUTION
KVALHEIM, OM
LIANG, YZ
[J]. ANALYTICAL CHEMISTRY, 1992, 64 (08) : 936 - 946

← 1 2 3 →