Application of several modified peak purity assays to real complex multicomponent mixtures by high-performance liquid chromatography with diode-array detection

被引：26

作者：

Frenich, AG ^{[1
]}

Torres-Lapasió, JR

De Braekeleer, K

Massart, DL

Vidal, JLM

Galera, MM

机构：

[1] Univ Almeria, Dept Hydrogeol & Analyt Chem, Almeria 04071, Spain

[2] Free Univ Brussels, ChemoAC, B-1090 Brussels, Belgium

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 855卷 / 02期

关键词：

needle search; orthogonal projection; SIMPLISMA; curve resolution; peak purity; chemometrics;

D O I：

10.1016/S0021-9673(99)00709-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Simple to use interactive self-modelling mixture analysis (SIMPLISMA), orthogonal projection (OPA) and Needle Search (NS) approaches have been applied to the determination of a number of compounds present in a complex multicomponent system. None of these three approaches succeeded completely when they were tested using the whole data matrix. When OPA and NS were applied to three simpler submatrices, obtained by dividing the total data matrix, and where a smaller number of compounds were present, better performance was achieved. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：487 / 499

页数：13

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