Neurological update: gliomas and other primary brain tumours in adults

被引：27

作者：

Brandner, Sebastian ^{[1
,2
]}

Jaunmuktane, Zane ^{[1
,3
]}

机构：

[1] Univ Coll London NHS Fdn Trust, Natl Hosp Neurol & Neurosurg, Div Neuropathol, Queen Sq, London WC1N 3BG, England

[2] UCL, Inst Neurol, Dept Neurodegenerat, Queen Sq, London WC1N 3BG, England

[3] UCL, Inst Neurol, Dept Mol Neurosci, Queen Sq, London WC1N 3BG, England

来源：

JOURNAL OF NEUROLOGY | 2018年 / 265卷 / 03期

关键词：

IDH; ATRX; TERT; EGFR; BRAF; Histone; Mutation; Astrocytoma; Oligodendroglioma; Glioblastoma; Ependymoma; BRAF inhibitor; Tumour heterogeneity; MGMT; Temozolomide; POSTERIOR-FOSSA EPENDYMOMA; IDH-MUTANT GLIOMA; LOW-GRADE GLIOMAS; MOLECULAR CLASSIFICATION; PILOCYTIC ASTROCYTOMA; GENETIC ALTERATIONS; CURRENT CONSENSUS; GENOMIC ANALYSIS; NERVOUS-SYSTEM; MUTATIONS;

D O I：

10.1007/s00415-017-8652-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The emerging understanding of molecular changes in a wide range of brain tumours has led to a significant shift in how these tumours are diagnosed, managed and treated. This article will provide a hands-on overview of the relevant biomarkers and their association with newly defined biological tumour entities.

引用

页码：717 / 727

页数：11

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