Polyvinyl alcohol nanofiber based three phase wound dressings for sustained wound healing applications

被引：70
作者：
Jatoi, Abdul Wahab [1 ,2 ]
Ogasawara, Hiroshi [3 ]
Kim, Ick Soo [4 ]
Ni, Qing-Qing [5 ]
机构：
[1] Shinshu Univ, Biosci & Text Technol Dept, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan
[2] Mehran Univ Engn & Technol, Dept Text Engn, Jamshoro 76062, Pakistan
[3] Shinshu Univ, Dept Life Sci, Ctr Res Supports Adv Sci, Div Gene Res, Tokida 3-15-1, Nagano, Nagano 3868567, Japan
[4] Shinshu Univ, ICCER, Nano Fus Technol Res Grp, Inst Fiber Engn IFES,Div Frontier Fibers, Tokida 3-15-1, Ueda, Nagano 3868567, Japan
[5] Shinshu Univ, Dept Mech Engn & Robot, Tokida 3-15-1, Ueda, Nagano 3868567, Japan
来源：
MATERIALS LETTERS | 2019年 / 241卷
关键词：
PVA nanofibers; AgNPs; Carbon nanotubes; Wound dressings; Antibacterial activities; Nanocomposites; COMPOSITE NANOFIBERS; FABRICATION; NANOPARTICLES; RELEASE; MATS;
D O I：
10.1016/j.matlet.2019.01.084
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Herein we present our research on a novel three phase antibacterial wound dressing prepared from carbon nanotubes, silver nanoparticles (AgNPs) and polyvinyl alcohol nanofibers. The AgNPs were generated on carbon nanotubes surfaces to synthesize carbon nanotubes-AgNP nanoparticles which were added into the polyvinyl alcohol nanofibers prior to electrospinning to prepare PVA/carbon nanotubes-AgNP composite nanofibers. All characterizations confirmed the three phase nanofiber architecture. Owing to growth of AgNPs on carbon nanotubes surfaces and embedding into PVA nanofibers the wound dressings are proposed for sustained and safer wound healing applications. The antibacterial test results confirmed excellent bactericidal and prolonged bacterial growth inhibition properties of the nanocomposites which suggest their suitability as sustained antibacterial wound dressing biomaterial. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页码：168 / 171
页数：4
相关论文
共 13 条
[1]   Purification and structural annealing of multiwalled carbon nanotubes at graphitization temperatures [J].
Andrews, R ;
Jacques, D ;
Qian, D ;
Dickey, EC .
CARBON, 2001, 39 (11) :1681-1687
[2]   Silver coated anionic cellulose nanofiber composites for an efficient antimicrobial activity [J].
Gopiraman, Mayakrishnan ;
Jatoi, Abdul Wahab ;
Hiromichi, Seki ;
Yamaguchi, Kyohei ;
Jeon, Han-Yong ;
Chung, Ill-Min ;
Kim, Ick Soo .
CARBOHYDRATE POLYMERS, 2016, 149 :51-59
[3]   Composite poly(vinyl alcohol)/poly(vinyl acetate) electrospun nanofibrous mats as a novel wound dressing matrix for controlled release of drugs [J].
Jannesari, Marziyeh ;
Varshosaz, Jaleh ;
Morshed, Mohammad ;
Zamani, Maedeh .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2011, 6
[4]   Antibacterial efficacy of poly(vinyl alcohol) composite nanofibers embedded with silver-anchored silica nanoparticles [J].
Jatoi, Abdul Wahab ;
Jo, Yun Kee ;
Lee, Hoik ;
Oh, Seong-Geun ;
Hwang, Dong Soo ;
Khatri, Zeeshan ;
Cha, Hyung Joon ;
Kim, Ick Soo .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2018, 106 (03) :1121-1128
[5]   Allantoin-loaded porous silica nanoparticles/polycaprolactone nanofiber composites: fabrication, characterization, and drug release properties [J].
Ke, Ma ;
Wahab, Jatoi Abdul ;
Hyunsik, Bang ;
Song, Kyung-Hun ;
Lee, Jung Soon ;
Gopiraman, Mayakrishnan ;
Kim, Ick Soo .
RSC ADVANCES, 2016, 6 (06) :4593-4600
[6]   Juniperus chinensis extracts loaded PVA nanofiber: Enhanced antibacterial activity [J].
Kim, Jeong Hwa ;
Lee, Hoik ;
Jatoi, Abdul Wahab ;
Im, Seung Soon ;
Lee, Jung Soon ;
Kim, Ick-Soo .
MATERIALS LETTERS, 2016, 181 :367-370
[7]   Facile route for preparation of silica-silver heterogeneous nanocomposite particles using alcohol reduction method [J].
Lee, Jong-Min ;
Kim, Dae-Wook ;
Kim, Tae-Hyun ;
Oh, Seong-Geun .
MATERIALS LETTERS, 2007, 61 (07) :1558-1562
[8]   Sodium alginate/poly(vinyl alcohol)/nano ZnO composite nanofibers for antibacterial wound dressings [J].
Shalumon, K. T. ;
Anulekha, K. H. ;
Nair, Sreeja V. ;
Nair, S. V. ;
Chennazhi, K. P. ;
Jayakumar, R. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2011, 49 (03) :247-254
[9]   Wound-dressing materials with antibacterial activity from electrospun polyurethane-dextran nanofiber mats containing ciprofloxacin HCl [J].
Unnithan, Afeesh R. ;
Barakat, Nasser A. M. ;
Pichiah, P. B. Tirupathi ;
Gnanasekaran, Gopalsamy ;
Nirmala, R. ;
Cha, Youn-Soo ;
Jung, Che-Hun ;
El-Newehy, Mohamed ;
Kim, Hak Yong .
CARBOHYDRATE POLYMERS, 2012, 90 (04) :1786-1793
[10]   Fabrication of Silk Fibroin/Eggshell Nanofiber Membranes for Facemasks [J].
Wahab, Jatoi Abdul ;
Xu, Gang ;
Lee, Hoik ;
Nam, Phan Duy ;
Wei, Kai ;
Kim, Seong Hun ;
Kim, Ick Soo .
FIBERS AND POLYMERS, 2016, 17 (11) :1776-1781
12