NIR-Triggered Release of Caged Nitric Oxide using Upconverting Nanostructured Materials

被引:161
作者
Garcia, John V. [1 ,2 ]
Yang, Jianping [2 ]
Shen, Dengke [2 ]
Yao, Chi [2 ]
Li, Xiaoming [2 ]
Wang, Rui [2 ]
Stucky, Galen D. [1 ]
Zhao, Dongyuan [2 ]
Ford, Peter C. [1 ]
Zhang, Fan [2 ]
机构
[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
[2] Fudan Univ, Dept Chem & Lab Adv Mat, Shanghai 200433, Peoples R China
基金
美国国家科学基金会;
关键词
upconversion; nanomaterials; NIR-triggered release; caged nitric oxides; photoactivation; EARTH FLUORIDE NANOCRYSTALS; ROUSSINS BLACK SALT; NEAR-INFRARED LIGHT; PHASE; PHOTOCHEMISTRY; LUMINESCENCE; REACTIVITY; COMPLEXES; NITROSYLS; DELIVERY;
D O I
10.1002/smll.201201213
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lanthanide-doped upconversion nanoparticles (UCNPs) mediate nitric oxide uncaging from Roussin's black salt anion Fe4S3(NO) 7- using NIR light from a simple diode laser operating continuously at 980 nm. This result offers a new paradigm for applications of multi-photon absorption in the therapeutic delivery of NO. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:3800 / 3805
页数:6
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