Prediction of noninertial focusing of red blood cells in Poiseuille flow

被引:6
作者
Hariprasad, Daniel S. [1 ]
Secomb, Timothy W. [2 ]
机构
[1] Univ New Mexico, Dept Chem & Biol Engn, Albuquerque, NM 87131 USA
[2] Univ Arizona, Dept Physiol, Tucson, AZ 85721 USA
来源
PHYSICAL REVIEW E | 2015年 / 92卷 / 03期
基金
美国国家卫生研究院;
关键词
MACROSCOPIC RIGID SPHERES; LATERAL MIGRATION; LIFT FORCE; MOTION; DEFORMATION; DYNAMICS; VESICLES; BEHAVIOR; PARTICLE; MODEL;
D O I
10.1103/PhysRevE.92.033008
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
The motions of a red blood cell in Poiseuille flows in a range of channel widths are simulated using a two-dimensional model. For a range of initial off-centerline distances in a 12-mu m channel, cell trajectories converge to a specific off-centerline position and exhibit tank-treading motions. This behavior coexists with initial positions that lead to migration towards the centerline. The predicted off-centerline focusing effect is shown to depend on the curvature of the flow profile and on interactions with both solid boundaries.
引用
收藏
页数:6
相关论文
共 30 条
  • [1] Simulated two-dimensional red blood cell motion, deformation, and partitioning in microvessel bifurcations
    Barber, Jared O.
    Alberding, Jonathan P.
    Restrepo, Juan M.
    Secomb, Timothy W.
    [J]. ANNALS OF BIOMEDICAL ENGINEERING, 2008, 36 (10) : 1690 - 1698
  • [2] Optimal lift force on vesicles near a compressible substrate
    Beaucourt, J
    Biben, T
    Misbah, C
    [J]. EUROPHYSICS LETTERS, 2004, 67 (04): : 676 - 682
  • [3] THE MOTION OF RIGID PARTICLES IN A SHEAR FLOW AT LOW REYNOLDS NUMBER
    BRETHERTON, FP
    [J]. JOURNAL OF FLUID MECHANICS, 1962, 14 (02) : 284 - 304
  • [4] Lift force and dynamical unbinding of adhering vesicles under shear flow
    Cantat, I
    Misbah, C
    [J]. PHYSICAL REVIEW LETTERS, 1999, 83 (04) : 880 - 883
  • [5] Noninertial lateral migration of vesicles in bounded Poiseuille flow
    Coupier, Gwennou
    Kaoui, Badr
    Podgorski, Thomas
    Misbah, Chaouqi
    [J]. PHYSICS OF FLUIDS, 2008, 20 (11)
  • [6] Vesicles in Poiseuille Flow
    Danker, Gerrit
    Vlahovska, Petia M.
    Misbah, Chaouqi
    [J]. PHYSICAL REVIEW LETTERS, 2009, 102 (14)
  • [7] The viscosity of the blood in narrow capillary tubes
    Fahraeus, R
    Lindqvist, T
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1931, 96 (03): : 562 - 568
  • [8] Fahraeus Robin., 1928, Klin Wochenschr, V7, P100
  • [9] Deformation and dynamics of red blood cells in flow through cylindrical microchannels
    Fedosov, Dmitry A.
    Peltomaeki, Matti
    Gompper, Gerhard
    [J]. SOFT MATTER, 2014, 10 (24) : 4258 - 4267
  • [10] Leukocyte margination in a model microvessel
    Freund, Jonathan B.
    [J]. PHYSICS OF FLUIDS, 2007, 19 (02)