Prediction of noninertial focusing of red blood cells in Poiseuille flow

被引:6
作者
Hariprasad, Daniel S. [1 ]
Secomb, Timothy W. [2 ]
机构
[1] Univ New Mexico, Dept Chem & Biol Engn, Albuquerque, NM 87131 USA
[2] Univ Arizona, Dept Physiol, Tucson, AZ 85721 USA
来源
PHYSICAL REVIEW E | 2015年 / 92卷 / 03期
基金
美国国家卫生研究院;
关键词
MACROSCOPIC RIGID SPHERES; LATERAL MIGRATION; LIFT FORCE; MOTION; DEFORMATION; DYNAMICS; VESICLES; BEHAVIOR; PARTICLE; MODEL;
D O I
10.1103/PhysRevE.92.033008
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
The motions of a red blood cell in Poiseuille flows in a range of channel widths are simulated using a two-dimensional model. For a range of initial off-centerline distances in a 12-mu m channel, cell trajectories converge to a specific off-centerline position and exhibit tank-treading motions. This behavior coexists with initial positions that lead to migration towards the centerline. The predicted off-centerline focusing effect is shown to depend on the curvature of the flow profile and on interactions with both solid boundaries.
引用
收藏
页数:6
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