Chronic norovirus infection in a transplant patient successfully treated with enterally administered immune globulin

被引:30
作者
Chagla, Zain [1 ]
Quirt, Jaclyn [2 ]
Woodward, Kevin [1 ]
Neary, John [3 ]
Rutherford, Candace [4 ]
机构
[1] McMaster Univ, Dept Infect Dis, Hamilton, ON L8N 1Y2, Canada
[2] McMaster Univ, Dept Med, Fac Hlth Sci, Internal Med Residency Off, Hamilton, ON L8S 4K1, Canada
[3] McMaster Univ, Dept Med, Hamilton, ON L8N 4A6, Canada
[4] Hamilton Reg Lab Med Program, Hamilton, ON L8N 4A6, Canada
关键词
Chronic norovirus; Immunoglobulin; Therapy; IMMUNOCOMPROMISED PATIENTS; IMMUNOGLOBULIN; ENTERITIS; EXCRETION; DIARRHEA;
D O I
10.1016/j.jcv.2013.06.009
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Norovirus infection causes a significant burden of morbidity and (in the developing world) mortality. In immunocompromised hosts, norovirus infection can become chronic, with devastating consequences. Unfortunately, therapeutic options for chronic disease are unproven, and treatment is largely supportive. We report a case of norovirus infection causing debilitating chronic gastroenteritis in a transplant patient that responded to a short course of enterally administered human immune globulin. (c) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:306 / 308
页数:3
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