β1-adrenoceptor Arg389Gly polymorphism and heart disease: marching toward clinical practice integration

被引:11
作者
McCrink, Katie A. [1 ]
Lymperopoulos, Anastasios [1 ]
机构
[1] Nova SE Univ, Coll Pharm, Dept Pharmaceut Sci, Lab Study Neurohormonal Control Circulat, Ft Lauderdale, FL 33314 USA
关键词
beta(1)-adrenergic receptor; beta-blocker; cardiovascular disease; dobutamine; drug response; GWAS; heart failure; hypertension; polymorphism; RECEPTOR GENE POLYMORPHISMS; DILATED CARDIOMYOPATHY; FAILURE; ASSOCIATION; POPULATION; VARIANTS; BETA-1;
D O I
10.2217/pgs.15.104
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:1035 / 1038
页数:4
相关论文
共 20 条
[1]   Interhelical Interaction and Receptor Phosphorylation Regulate the Activation Kinetics of Different Human β1-Adrenoceptor Variants [J].
Ahles, Andrea ;
Rodewald, Fabian ;
Rochais, Francesca ;
Buenemann, Moritz ;
Engelhardt, Stefan .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (03) :1760-1769
[2]   Polymorphic Variants of Adrenoceptors: Pharmacology, Physiology, and Role in Diseases [J].
Ahles, Andrea ;
Engelhardt, Stefan .
PHARMACOLOGICAL REVIEWS, 2014, 66 (03) :598-637
[3]   The Arg389GIy beta1-adrenoceptor polymorphism and catecholamine effects on plasma-renin activity [J].
Bruck, H ;
Leineweber, K ;
Ternme, T ;
Weber, M ;
Heusch, G ;
Philipp, T ;
Brodde, OE .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (11) :2111-2115
[4]   GPCR signaling and cardiac function [J].
Capote, Leany A. ;
Perez, Roberto Mendez ;
Lymperopoulos, Anastasios .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 763 :143-148
[5]   Adrenergic Signaling Polymorphisms and Their Impact on Cardiovascular Disease [J].
Dorn, Gerald W., II .
PHYSIOLOGICAL REVIEWS, 2010, 90 (03) :1013-1062
[6]   β1-adrenergic receptor gene polymorphisms in Mexican patients with idiopathic dilated cardiomyopathy [J].
Fragoso, Jose Manuel ;
Rodriguez-Perez, Jose Manuel ;
Gonzalez, Jaime ;
Cruz, David ;
Perez-Mendez, Oscar ;
Garcia, Jose de Jesus ;
de la Pena, Aurora ;
Arce, Minerva ;
Reyes, Pedro A. ;
Vargas-Alarcon, Gilberto .
EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2006, 80 (03) :279-282
[7]   New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism [J].
Horikoshi, Momoko ;
Yaghootkar, Hanieh ;
Mook-Kanamori, Dennis O. ;
Sovio, Ulla ;
Taal, H. Rob ;
Hennig, Branwen J. ;
Bradfield, Jonathan P. ;
St Pourcain, Beate ;
Evans, David M. ;
Charoen, Pimphen ;
Kaakinen, Marika ;
Cousminer, Diana L. ;
Lehtimaki, Terho ;
Kreiner-Moller, Eskil ;
Warrington, Nicole M. ;
Bustamante, Mariona ;
Feenstra, Bjarke ;
Berry, Diane J. ;
Thiering, Elisabeth ;
Pfab, Thiemo ;
Barton, Sheila J. ;
Shields, Beverley M. ;
Kerkhof, Marjan ;
van Leeuwen, Elisabeth M. ;
Fulford, Anthony J. ;
Kutalik, Zoltan ;
Zhao, Jing Hua ;
den Hoed, Marcel ;
Mahajan, Anubha ;
Lindi, Virpi ;
Goh, Liang-Kee ;
Hottenga, Jouke-Jan ;
Wu, Ying ;
Raitakari, Olli T. ;
Harder, Marie N. ;
Meirhaeghe, Aline ;
Ntalla, Ioanna ;
Salem, Rany M. ;
Jameson, Karen A. ;
Zhou, Kaixin ;
Monies, Dorota M. ;
Lagou, Vasiliki ;
Kirin, Mirna ;
Heikkinen, Jani ;
Adair, Linda S. ;
Alkuraya, Fowzan S. ;
Al-Odaib, Ali ;
Amouyel, Philippe ;
Andersson, Ehm Astrid ;
Bennett, Amanda J. .
NATURE GENETICS, 2013, 45 (01) :76-U115
[8]   The Arg389Gly β1-adrenoceptor gene polymorphism influences the acute effects of β-adrenoceptor blockade on contractility in the human heart [J].
Huntgeburth, Michael ;
La Rosee, Karl ;
ten Freyhaus, Henrik ;
Boehm, Michael ;
Schnabel, Petra ;
Hellmich, Martin ;
Rosenkranz, Stephan .
CLINICAL RESEARCH IN CARDIOLOGY, 2011, 100 (08) :641-647
[9]   Suppressive effect of the Gly389 allele of the β1-adrenergic receptor gene on the occurrence of ventricular tachycardia in dilated cardiomyopathy [J].
Iwai, C ;
Akita, H ;
Shiga, N ;
Takai, E ;
Miyamoto, Y ;
Shimizu, M ;
Kawai, H ;
Takarada, A ;
Kajiya, T ;
Yokoyama, M .
CIRCULATION JOURNAL, 2002, 66 (08) :723-728
[10]   Functional effects of β1-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without β-blocker administration [J].
Kindermann, Michael ;
Seeland, Ute ;
Ruhnke, Patrick ;
Boehm, Michael ;
Maack, Christoph .
CLINICAL RESEARCH IN CARDIOLOGY, 2011, 100 (02) :129-137