Silencing stemness in T cell differentiation

被引：16

作者：

Henning, Amanda N. ^{[1
,2
]}

Klebanoff, Christopher A. ^{[3
,4
,5
]}

Restifo, Nicholas P. ^{[1
,2
]}

机构：

[1] NCI, Ctr Cell Based Therapy, NIH, Bethesda, MD 20892 USA

[2] NCI, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

[3] MSKCC, Ctr Cell Engn, New York, NY 10065 USA

[4] MSKCC, Dept Med, New York, NY 10065 USA

[5] MSKCC, Parker Inst Canc Immunotherapy, New York, NY 10065 USA

来源：

SCIENCE | 2018年 / 359卷 / 6372期

关键词：

LINEAGE RELATIONSHIP; EFFECTOR;

D O I：

10.1126/science.aar5541

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：163 / 164

页数：2

共 15 条

[1] Lineage relationship of CD8+ T cell subsets is revealed by progressive changes in the epigenetic landscape [J].

Crompton, Joseph G. ;

Narayanan, Manikandan ;

Cuddapah, Suresh ;

Roychoudhuri, Rahul ;

Ji, Yun ;

Yang, Wenjing ;

Patel, Shashank J. ;

Sukumar, Madhusudhanan ;

Palmer, Douglas C. ;

Peng, Weiqun ;

Wang, Ena ;

Marincola, Francesco M. ;

Klebanoff, Christopher A. ;

Zhao, Keji ;

Tsang, John S. ;

Gattinoni, Luca ;

Restifo, Nicholas P. .

CELLULAR & MOLECULAR IMMUNOLOGY, 2016, 13 (04) :502-513

[2] Dedifferentiation and reprogramming: origins of cancer stem cells [J].

Friedmann-Morvinski, Dinorah ;

Verma, Inder M. .

EMBO REPORTS, 2014, 15 (03) :244-253

[3] Paths to stemness: building the ultimate antitumour T cell [J].

Gattinoni, Luca ;

Klebanoff, Christopher A. ;

Restifo, Nicholas P. .

NATURE REVIEWS CANCER, 2012, 12 (10) :671-684

[4] A human memory T cell subset with stem cell-like properties [J].

Gattinoni, Luca ;

Lugli, Enrico ;

Ji, Yun ;

Pos, Zoltan ;

Paulos, Chrystal M. ;

Quigley, Maire F. ;

Almeida, Jorge R. ;

Gostick, Emma ;

Yu, Zhiya ;

Carpenito, Carmine ;

Wang, Ena ;

Douek, Daniel C. ;

Price, David A. ;

June, Carl H. ;

Marincola, Francesco M. ;

Roederer, Mario ;

Restifo, Nicholas P. .

NATURE MEDICINE, 2011, 17 (10) :1290-U325

[5] Serial Transfer of Single-Cell-Derived Immunocompetence Reveals Stemness of CD8+ Central Memory T Cells [J].

Graef, Patricia ;

Buchholz, Veit R. ;

Stemberger, Christian ;

Flossdorf, Michael ;

Henkel, Lynette ;

Schiemann, Matthias ;

Drexler, Ingo ;

Hoefer, Thomas ;

Riddell, Stanley R. ;

Busch, Dirk H. .

IMMUNITY, 2014, 41 (01) :116-126

[6] Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8+ T Cell Terminal Differentiation and Loss of Multipotency [J].

Gray, Simon M. ;

Amezquita, Robert A. ;

Guan, Tianxia ;

Kleinstein, Steven H. ;

Kaech, Susan M. .

IMMUNITY, 2017, 46 (04) :596-608

[7] Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells [J].

Hawkins, R. David ;

Hon, Gary C. ;

Lee, Leonard K. ;

Ngo, QueMinh ;

Lister, Ryan ;

Pelizzola, Mattia ;

Edsall, Lee E. ;

Kuan, Samantha ;

Luu, Ying ;

Klugman, Sarit ;

Antosiewicz-Bourget, Jessica ;

Ye, Zhen ;

Espinoza, Celso ;

Agarwahl, Saurabh ;

Shen, Li ;

Ruotti, Victor ;

Wang, Wei ;

Stewart, Ron ;

Thomson, James A. ;

Ecker, Joseph R. ;

Ren, Bing .

CELL STEM CELL, 2010, 6 (05) :479-491

[8] Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing [J].

Kakaradov, Boyko ;

Arsenio, Janilyn ;

Widjaja, Christella E. ;

He, Zhaoren ;

Aigner, Stefan ;

Metz, Patrick J. ;

Yu, Bingfei ;

Wehrens, Ellen J. ;

Lopez, Justine ;

Kim, Stephanie H. ;

Zuniga, Elina I. ;

Goldrath, Ananda W. ;

Chang, John T. ;

Yeo, Gene W. .

NATURE IMMUNOLOGY, 2017, 18 (04) :422-+

[9] Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy [J].

Klebanoff, Christopher A. ;

Scott, Christopher D. ;

Leonardi, Anthony J. ;

Yamamoto, Tori N. ;

Cruz, Anthony C. ;

Ouyang, Claudia ;

Ramaswamy, Madhu ;

Roychoudhuri, Rahul ;

Ji, Yun ;

Eil, Robert L. ;

Sukumar, Madhusudhanan ;

Crompton, Joseph G. ;

Palmer, Douglas C. ;

Borman, Zachary A. ;

Clever, David ;

Thomas, Stacy K. ;

Patel, Shashankkumar ;

Yu, Zhiya ;

Muranski, Pawel ;

Liu, Hui ;

Wang, Ena ;

Marincola, Francesco M. ;

Gros, Alena ;

Gattinoni, Luca ;

Rosenberg, Steven A. ;

Siegel, Richard M. ;

Restifo, Nicholas P. .

JOURNAL OF CLINICAL INVESTIGATION, 2016, 126 (01) :318-334

[10] De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation [J].

Ladle, Brian H. ;

Li, Kun-Po ;

Phillips, Maggie J. ;

Pucsek, Alexandra B. ;

Haile, Azeb ;

Powell, Jonathan D. ;

Jaffee, Elizabeth M. ;

Hildeman, David A. ;

Gamper, Christopher J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (38) :10631-10636

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