Facile fabrication of carbonaceous nanospheres loaded with silver nanoparticles as antibacterial materials

被引:74
|
作者
Cui, Jianghu [1 ]
Hu, Chaofan [1 ]
Yang, Yunhua [1 ]
Wu, Yongjian [1 ]
Yang, Lufeng [1 ]
Wang, Yaling [1 ]
Liu, Yingliang [1 ]
Jiang, Zhenyou [2 ]
机构
[1] Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Dept Microbiol & Immunol, Guangzhou 510632, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
CENTRAL VENOUS CATHETERS; IN-VITRO EVALUATION; CYTOTOXICITY; GENOTOXICITY; COMPOSITES; EXPRESSION; APOPTOSIS; COATINGS; RELEASE;
D O I
10.1039/c2jm16441h
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Carbonaceous nanospheres with silver nanoparticles (CNs-Ag) composites were prepared by a facile and low cost method. Silver nanoparticles were successfully loaded onto the surface of carbonaceous nanospheres, which were examined by X-ray diffraction, UV-vis spectra, transmission electron microscopy, energy dispersive spectrometry and X-ray photoelectron spectroscopy. The antibacterial properties of the CNs-Ag composites were investigated by the kinetics of bacterial growth and a disk-diffusion test. The cytotoxicity of the CNs-Ag composites was determined by MTT assay. The results suggest that the obtained CNs-Ag composites exhibit enhanced antibacterial properties and lower cytotoxicity in comparison with silver nanoparticles. The composites may be alternative antibacterial materials with mild cytotoxicity in biomedical fields.
引用
收藏
页码:8121 / 8126
页数:6
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