Trichothecenes: From Simple to Complex Mycotoxins

被引：356
作者：
McCormick, Susan P. [1 ]
Stanley, April M. [2 ]
Stover, Nicholas A. [2 ]
Alexander, Nancy J. [1 ]
机构：
[1] USDA ARS, Natl Ctr Agr Utilizat Res, Peoria, IL 61604 USA
[2] Bradley Univ, Dept Biol, Peoria, IL 61625 USA
来源：
TOXINS | 2011年 / 3卷 / 07期
关键词：
trichothecenes; mycotoxins; Type A; Type B; macrocyclic; d-type; t-type; toxin biosynthesis; FUSARIUM-SPOROTRICHIOIDES ENCODES; EUKARYOTIC PROTEIN-SYNTHESIS; T-2; TOXIN; CYTOCHROME-P450; MONOOXYGENASE; MACROCYCLIC TRICHOTHECENES; GENE-CLUSTER; FUNCTIONAL-CHARACTERIZATION; 3-O-ACETYLTRANSFERASE GENE; TRICHODERMA-HARZIANUM; MYROTHECIUM-RORIDUM;
D O I：
10.3390/toxins3070802
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
As the world's population grows, access to a safe food supply will continue to be a global priority. In recent years, the world has experienced an increase in mycotoxin contamination of grains due to climatic and agronomic changes that encourage fungal growth during cultivation. A number of the molds that are plant pathogens produce trichothecene mycotoxins, which are known to cause serious human and animal toxicoses. This review covers the types of trichothecenes, their complexity, and proposed biosynthetic pathways of trichothecenes.
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页码：802 / 814
页数：13
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