Age-dependent phosphate homoeostasis is regulated by a circulating factor

被引:1
作者
Matsumoto, N
Komatsu, Y
Hattori, M
Shiraga, H
Ito, K
机构
[1] Tokyo Womens Med Univ, Dept Pediat Nephrol, Tokyo, Japan
[2] St Lukes Int Hosp, Dept Med, Tokyo, Japan
关键词
phosphate; PHEX gene; development;
D O I
10.1159/000065447
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
To evaluate the age-dependent phosphate homeostasis, we studied the serum inorganic phosphate (P-i) concentration in 78 recipients, aged 5-25 years, a year after renal transplantation (RT). The significant age-dependent decline of the serum P-i concentration was observed in recipients (p < 0.0001) as well as in normal children. Our study revealed that a circulating factor may play a central role in the age-dependent change of phosphate regulation in human. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码:931 / 932
页数:2
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