Syntheses, crystal structures, and urease inhibitory properties of copper(II) and zinc(II) complexes with 2-bromo-4-chloro-6-[(2-dimethylaminoethylimino)methyl]phenol

被引：38

作者：

Wang, Chen-Yi ^{[1
]}

机构：

[1] Huzhou Univ, Dept Chem, Huzhou 313000, Peoples R China

来源：

JOURNAL OF COORDINATION CHEMISTRY | 2009年 / 62卷 / 17期

关键词：

Schiff base; Copper; Zinc; Crystal structure; Urease inhibitory property; SUPEROXIDE-DISMUTASE ACTIVITY; KLEBSIELLA-AEROGENES UREASE; METAL-COMPLEXES; BASE COMPLEXES; LIGANDS; FREQUENCIES; SPECTRA; ENZYME; ACID;

D O I：

10.1080/00958970902946702

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new copper(II) complex, [CuL(1,1-N3)]n (1), and a new zinc(II) complex, [ZnL(2-acetato-O, O')2]n (2) (HL = 2-bromo-4-chloro-6-[(2-dimethylaminoethylimino)methyl]phenol), were prepared and characterized by elemental analyses, infrared spectroscopy, and single-crystal X-ray diffraction. Complex 1 is an end-on azide-bridged polynuclear copper(II) complex and 2 is a syn-anti bidentate acetate-bridged polynuclear zinc(II) complex. Each metal in the complex is five-coordinate with square-pyramidal geometry. Complex 1 shows good urease inhibitory properties, while 2 does not.

引用

页码：2860 / 2868

页数：9

共 25 条

[1] Crystal structure and superoxide dismutase activity of [Cu(imidazole)2(quinoline)Cl2]•0.5[Cu(imidazole)4Cl2] [J].

Anacona, JR ;

Gutierrez, C ;

Nusetti, O ;

Loroño, D .

JOURNAL OF COORDINATION CHEMISTRY, 2002, 55 (12) :1433-1439

[2]

[Anonymous], 2002, SMART CARD INTEGRATI

[3] Synthesis and structure of mononuclear and binuclear zinc(II) compartmental macrocyclic complexes [J].

Atkins, AJ ;

Black, D ;

Finn, RL ;

Marin-Becerra, A ;

Blake, AJ ;

Ruiz-Ramirez, L ;

Li, WS ;

Schröder, M .

DALTON TRANSACTIONS, 2003, (09) :1730-1737

[4] SYNTHESIS OF SOME TRANSITION-METAL COMPLEXES DERIVED FROM 1-VALEROYL-4-PHENYL-3-THIOSEMICARBAZIDE [J].

BEKHEIT, MM ;

IBRAHIM, KM .

SYNTHESIS AND REACTIVITY IN INORGANIC AND METAL-ORGANIC CHEMISTRY, 1986, 16 (08) :1135-1147

[5] New method for the synthesis of a mononucleating cyclic peptide ligand, crystal structures of its Ni, Zn, Cu, and Co complexes, and their inhibitory bioactivity against urease [J].

Cheng, Kui ;

You, Zhong-Lu ;

Zhu, Hai-Liang .

AUSTRALIAN JOURNAL OF CHEMISTRY, 2007, 60 (05) :375-379

[6] RELATIONSHIPS BETWEEN THE CARBON-OXYGEN STRETCHING FREQUENCIES OF CARBOXYLATO COMPLEXES AND THE TYPE OF CARBOXYLATE COORDINATION [J].

DEACON, GB ;

PHILLIPS, RJ .

COORDINATION CHEMISTRY REVIEWS, 1980, 33 (03) :227-250

[7] Synthesis, catalase, superoxide dismutase and antitumour activities of copper(II) carboxylate complexes incorporating benzimidazole, 1,10-phenanthroline and bipyridine ligands:: X-ray crystal structures of [Cu(BZA)2(bipy)(H2O)], [Cu(SalH)2(BZDH)2] and [Cu(CH3COO)2(5,6-DMBZDH)2] (SalH2 =salicylic acid; BZAH = benzoic acid; BZDH = benzimidazole and 5,6-DMBZDH=5,6-dimethylbenzimidazole) [J].

Devereux, Michael ;

O'Shea, Denis ;

O'Connor, Mark ;

Grehan, Helen ;

Connor, Gavin ;

McCann, Malachy ;

Rosair, Georgina ;

Lyng, Fiona ;

Kellett, Andrew ;

Walsh, Maureen ;

Egan, Denise ;

Thati, Bhumika .

POLYHEDRON, 2007, 26 (15) :4073-4084

[8] Di- and poly-nuclear zinc(II) Schiff base complexes:: synthesis, structural studies and reaction with an α-amino acid [J].

Erxleben, A ;

Hermann, J .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 2000, (04) :569-575

[9] Complexation, structure, and superoxide dismutase activity of the imidazolate-bridged dinuclear copper moiety with β-cyclodextrin and its guanidinium-containing derivative [J].

Fu, H ;

Zhou, YH ;

Chen, WL ;

Deqing, ZG ;

Tong, ML ;

Ji, LN ;

Mao, ZW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (15) :4924-4925

[10] THE C=N STRETCHING FREQUENCY IN INFRARED SPECTRA OF SCHIFFS BASE COMPLEXES .I. COPPER COMPLEXES OF SALICYLIDENE ANILINES [J].

KOVACIC, JE .

SPECTROCHIMICA ACTA PART A-MOLECULAR SPECTROSCOPY, 1967, A 23 (01) :183-&

← 1 2 3 →