Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis

被引:736
作者
Pappas, Georgios [1 ,2 ]
Roussos, Nikos [2 ]
Falagas, Matthew E. [2 ,3 ,4 ]
机构
[1] Inst Continuing Med Educ Ioannina, Ioannina 45333, Greece
[2] Alfa Inst Biomed Sci, Athens, Greece
[3] Henry Dunant Hosp, Dept Med, Athens, Greece
[4] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA
关键词
Toxoplasmosis; Pregnancy; Seroprevalence; RISK-FACTORS; SEROLOGIC PROFILE; CHILDBEARING AGE; EXPOSURE FACTORS; UNITED-STATES; WOMEN; INFECTION; PREVALENCE; ANTIBODIES; POPULATION;
D O I
10.1016/j.ijpara.2009.04.003
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Toxoplasma gondii's importance for humans refers mainly to primary infection during pregnancy. resulting in abortion/stillbirth or congenital toxoplasmosis. The authors sought to evaluate the current global status of T. gondii seroprevalence and its correlations with risk factors, environmental and socioeconomic parameters. Literature published during the last decade on toxoplasmosis seroprevalence, in women who were pregnant or of childbearing age, was retrieved. A total of 99 studies were eligible; a further 36 studies offered seroprevalence data from regions/countries for which no data on pregnancy/child bearing age were available. Foci of high prevalence exist in Latin America, parts of Eastern/Central Europe, the Middle East, parts of south-east Asia and Africa. Regional seroprevalence variations relate to individual subpopulations' religious and socioeconomic practices. A trend towards lower seroprevalence is observed in many European countries and the United States of America (USA). There is no obvious climate-related gradient, excluding North and Latin America. Immigration has affected local prevalence in certain countries. We further sought to recognise specific risk factors related to seropositivity; however, such risk factors are not reported systematically. Population awareness may affect recognition of said risks. Global toxoplasmosis seroprevalence is continuingly evolving, subject to regional socioeconomic parameters and population habits. Awareness of these seroprevalence trends, particularly in the case of women of childbearing age, may allow proper public health policies to be enforced, targeting in particular seronegative women of childbearing age in high seroprevalence areas. (C) 2009 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1385 / 1394
页数:10
相关论文
共 146 条
[1]  
Abdi J, 2008, IRAN J PARASITOL, V3, P34
[2]   Seroprevalence and epidemiological correlates of Toxoplasma gondii infections among patients referred for hospital-based serological testing in Doha, Qatar [J].
Abu-Madi, Marawan A. ;
Al-Molawi, Naema ;
Behnke, Jerzy M. .
PARASITES & VECTORS, 2008, 1 (1)
[3]  
ACOSTABAS C, 2001, REV BIOMED, V12, P250
[4]  
Adou-Bryn K D, 2004, Bull Soc Pathol Exot, V97, P345
[5]  
Akoijam Brogen Singh, 2002, J Indian Med Assoc, V100, P591
[6]  
Al-Qurashi AR, 2001, SAUDI MED J, V22, P13
[7]  
ALEXANDROU ME, 2002, CLIN MICROBIOL INFEC, V8, P282
[8]   Seroepidemiology of Toxoplasma gondii infection in pregnant women in a public hospital in northern Mexico [J].
Alvarado-Esquivel, Cosme ;
Sifuentes-Alvarez, Antonio ;
Guadalupe Narro-Duarte, Sergio ;
Estrada-Martinez, Sergio ;
Humberto Diaz-Garcia, Juan ;
Liesenfeld, Oliver ;
Arturo Martinez-Garcia, Sergio ;
Canales-Molina, Arturo .
BMC INFECTIOUS DISEASES, 2006, 6 (1)
[9]   Prevalence and incidence in Albacete, Spain, of Toxoplasma gondii infection in women of childbearing age.: Differences between immigrant and non-immigrant (2001-2007) [J].
Alvarez, Joaquin-Bartolome ;
Serrano, Maria Martinez ;
Parrado, Laura Moreno ;
Ortuno, Santiago Lorente ;
Sanchez, Maria Dolores Crespo .
REVISTA ESPANOLA DE SALUD PUBLICA, 2008, 82 (03) :333-342
[10]   A preliminary study of the significance of partial tones in the localization of sound [J].
Angell, JR .
PSYCHOLOGICAL REVIEW, 1903, 10 :1-14