Non-pharmacological treatment of hypertension in primary health care: a 2-year open randomized controlled trial of lifestyle intervention against hypertension in eastern Finland

被引:55
作者
Kastarinen, MJ
Puska, PM
Korhonen, MH
Mustonen, JN
Salomaa, VV
Sundvall, JE
Tuomilehto, JO
Uusitupa, MI
Nissinen, AM
机构
[1] Univ Kuopio, Dept Publ Hlth & Gen Practice, FIN-70211 Kuopio, Finland
[2] WHO, Dept Non Communicable Dis Prevent & Hlth Promot, CH-1211 Geneva, Switzerland
[3] Univ Kuopio, Dept Clin Nutr, FIN-70211 Kuopio, Finland
[4] N Karelia Cent Hosp, Dept Internal Med, Joensuu, Finland
[5] Natl Publ Hlth Inst, Dept Epidemiol & Hlth Promot, Helsinki, Finland
[6] Natl Publ Hlth Inst, Dept Hlth & Funct Capac, Helsinki, Finland
[7] Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland
关键词
hypertension; randomized controlled trial; life change events;
D O I
10.1097/00004872-200212000-00031
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Objective To assess whether lifestyle counselling is effective in non-pharmacological treatment of hypertension in primary health care. Design Open randomized controlled trial. Setting Ten municipal primary health care centres in eastern Finland. Patients Seven hundred and fifteen subjects aged 25-74 years with systolic blood pressure 140-179 mmHg and/or diastolic blood pressure 90-109 mmHg or anti hypertensive drug treatment Interventions Systematic health counselling given by local public health nurses for 2 years. Main outcome measures Blood pressure, lipids and lifestyle data were collected annually. Results Among participants with no antihypertensive drug treatment, the net reductions after 1 year both in systolic blood pressure [-2.6 mmHg; 95% confidence interval (CI), -4.7 to -0.5 mmHg] and in diastolic blood pressure (-2.7 mmHg; 95% CI, -4.0 to -1.4 mmHg) were significant in favour of the intervention group. This difference in blood pressure change was maintained during the second year. In participants with antihypertensive drug treatment, no significant difference in blood pressure reduction was seen between the groups during the study. Conclusions A relatively modest, but systematic counselling in primary health care can, at least among untreated hypertensive subjects, produce reductions in blood pressure levels that are modest for the individual, but very important from the public health point of view. (C) 2002 Lippincott Williams Wilkins.
引用
收藏
页码:2505 / 2512
页数:8
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