Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients

被引：10
作者：
Bellanger, Anne-Pauline [1 ,3 ]
Berceanu, Ana [4 ]
Scherer, Emeline [2 ,3 ]
Desbrosses, Yohan [4 ]
Daguindau, Etienne [4 ]
Rocchi, Steffi [2 ]
Millon, Laurence [2 ,3 ]
机构：
[1] Univ Hosp, Diag Invas Fungal Infect, Besancon, France
[2] Univ Hosp, Besancon, France
[3] Franche Comte Univ, Besancon, France
[4] Besancon Univ Hosp, Besancon, France
来源：
EMERGING INFECTIOUS DISEASES | 2019年 / 25卷 / 09期
关键词：
INFECTIONS;
D O I：
10.3201/eid2509.190598
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We present 2 fatal cases of invasive fungal disease with isavuconazole treatment failure in immunocompromised patients: one with a TR34-L98H azole-resistant Aspergillus fumigatus isolate and the other a Rhizomucor-A. fumigatus co-infection. Such patients probably require surveillance by galactomannan antigen detection and quantitative PCRs for A. fumigatus and Mucorales fungi.
引用
收藏
页码：1778 / 1779
页数：2
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