GenomeHubs: simple containerized setup of a custom Ensembl database and web server for any species

被引:10
作者
Challis, Richard J. [1 ]
Kumar, Sujai [1 ]
Stevens, Lewis [1 ]
Blaxter, Mark [1 ]
机构
[1] Univ Edinburgh, Inst Evolutionary Biol, Ashworth Labs, Charlotte Auerbach Rd, Edinburgh EH9 3FL, Midlothian, Scotland
来源
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION | 2017年
基金
英国生物技术与生命科学研究理事会;
关键词
RESOURCE; GENOMICS; BROWSER;
D O I
10.1093/database/bax039
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
As the generation and use of genomic datasets is becoming increasingly common in all areas of biology, the need for resources to collate, analyse and present data from one or more genome projects is becoming more pressing. The Ensembl platform is a powerful tool to make genome data and cross-species analyses easily accessible through a web interface and a comprehensive application programming interface. Here we introduce GenomeHubs, which provide a containerized environment to facilitate the setup and hosting of custom Ensembl genome browsers. This simplifies mirroring of existing content and import of new genomic data into the Ensembl database schema. GenomeHubs also provide a set of analysis containers to decorate imported genomes with results of standard analyses and functional annotations and support export to flat files, including EMBL format for submission of assemblies and annotations to International Nucleotide Sequence Database Collaboration.
引用
收藏
页数:9
相关论文
共 28 条
[1]   The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera [J].
Ahola, Virpi ;
Lehtonen, Rainer ;
Somervuo, Panu ;
Salmela, Leena ;
Koskinen, Patrik ;
Rastas, Pasi ;
Valimaki, Niko ;
Paulin, Lars ;
Kvist, Jouni ;
Wahlberg, Niklas ;
Tanskanen, Jaakko ;
Hornett, Emily A. ;
Ferguson, Laura C. ;
Luo, Shiqi ;
Cao, Zijuan ;
de Jong, Maaike A. ;
Duplouy, Anne ;
Smolander, Olli-Pekka ;
Vogel, Heiko ;
McCoy, Rajiv C. ;
Qian, Kui ;
Chong, Wong Swee ;
Zhang, Qin ;
Ahmad, Freed ;
Haukka, Jani K. ;
Joshi, Aruj ;
Salojarvi, Jarkko ;
Wheat, Christopher W. ;
Grosse-Wilde, Ewald ;
Hughes, Daniel ;
Katainen, Riku ;
Pitkanen, Esa ;
Ylinen, Johannes ;
Waterhouse, Robert M. ;
Turunen, Mikko ;
Vaharautio, Anna ;
Ojanen, Sami P. ;
Schulman, Alan H. ;
Taipale, Minna ;
Lawson, Daniel ;
Ukkonen, Esko ;
Makinen, Veli ;
Goldsmith, Marian R. ;
Holm, Liisa ;
Auvinen, Petri ;
Frilander, Mikko J. ;
Hanski, Ilkka .
NATURE COMMUNICATIONS, 2014, 5
[2]   Reminder to deposit DNA sequences [J].
Blaxter, Mark ;
Danchin, Antoine ;
Savakis, Babis ;
Fukami-Kobayashi, Kaoru ;
Kurokawa, Ken ;
Sugano, Sumio ;
Roberts, Richard J. ;
Salzberg, Steven L. ;
Wu, Chung-I .
SCIENCE, 2016, 352 (6287) :780-780
[3]  
Boutet E, 2016, METHODS MOL BIOL, V1374, P23, DOI 10.1007/978-1-4939-3167-5_2
[4]  
Challis R., 2017, RJCHALLIS CODON USAG
[5]  
Challis R., 2017, RJCHALLIS ASSEMBLY S
[6]  
Challis RJ, 2016, LEPBASE LEPIDOPTERAN, DOI [DOI 10.1101/056994, 10.1101/056994]
[7]   The International Nucleotide Sequence Database Collaboration [J].
Cochrane, Guy ;
Karsch-Mizrachi, Ilene ;
Takagi, Toshihisa .
NUCLEIC ACIDS RESEARCH, 2016, 44 (D1) :D48-D50
[8]   The Genome of Winter Moth (Operophtera brumata) Provides a Genomic Perspective on Sexual Dimorphism and Phenology [J].
Derks, Martijn F. L. ;
Smit, Sandra ;
Salis, Lucia ;
Schijlen, Elio ;
Bossers, Alex ;
Mateman, Christa ;
Pijl, Agata S. ;
de Ridder, Dick ;
Groenen, Martien A. M. ;
Visser, Marcel E. ;
Megens, Hendrik-Jan .
GENOME BIOLOGY AND EVOLUTION, 2015, 7 (08) :2321-2332
[9]   Avianbase: a community resource for bird genomics [J].
Eoery, Lel ;
Gilbert, M. Thomas P. ;
Li, Cai ;
Li, Bo ;
Archibald, Alan ;
Aken, Bronwen L. ;
Zhang, Guojie ;
Jarvis, Erich ;
Flicek, Paul ;
Burt, David W. .
GENOME BIOLOGY, 2015, 16
[10]   InterPro in 2017-beyond protein family and domain annotations [J].
Finn, Robert D. ;
Attwood, Teresa K. ;
Babbitt, Patricia C. ;
Bateman, Alex ;
Bork, Peer ;
Bridge, Alan J. ;
Chang, Hsin-Yu ;
Dosztanyi, Zsuzsanna ;
El-Gebali, Sara ;
Fraser, Matthew ;
Gough, Julian ;
Haft, David ;
Holliday, Gemma L. ;
Huang, Hongzhan ;
Huang, Xiaosong ;
Letunic, Ivica ;
Lopez, Rodrigo ;
Lu, Shennan ;
Marchler-Bauer, Aron ;
Mi, Huaiyu ;
Mistry, Jaina ;
Natale, Darren A. ;
Necci, Marco ;
Nuka, Gift ;
Orengo, Christine A. ;
Park, Youngmi ;
Pesseat, Sebastien ;
Piovesan, Damiano ;
Potter, Simon C. ;
Rawlings, Neil D. ;
Redaschi, Nicole ;
Richardson, Lorna ;
Rivoire, Catherine ;
Sangrador-Vegas, Amaia ;
Sigrist, Christian ;
Sillitoe, Ian ;
Smithers, Ben ;
Squizzato, Silvano ;
Sutton, Granger ;
Thanki, Narmada ;
Thomas, Paul D. ;
Tosatto, Silvio C. E. ;
Wu, Cathy H. ;
Xenarios, Ioannis ;
Yeh, Lai-Su ;
Young, Siew-Yit ;
Mitchell, Alex L. .
NUCLEIC ACIDS RESEARCH, 2017, 45 (D1) :D190-D199