NMR analysis of polyester urethane end groups and solid-phase hydrolysis kinetics

被引：14

作者：

LeMaster, DM ^{[1
]}

Hernández, G ^{[1
]}

机构：

[1] Univ Calif Los Alamos Natl Lab, Biosci Div, Grp BS1, Los Alamos, NM 87545 USA

来源：

MACROMOLECULES | 2000年 / 33卷 / 10期

关键词：

D O I：

10.1021/ma992030w

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Multidimensional heteronuclear solution NMR is used for end group analysis and solid-phase hydrolysis kinetics determination on a 40 kDa commercial linear polyester urethane. Pure autocatalytic acid cleavage of the ester Linkages is observed under humid atmosphere. T-1 and T-2 relaxation effects on 2D H-1-C-13 correlation spectra are analyzed so as to provide quantitative interpretation of cross-peak intensity for relative concentration measurements. A 3D C-18-purged H-1-H-1-C-13 TOCSY-HSQC experiment serves to establish extensive H-1 and C-13 spin coupling connectivities at a level of 1-2 sites per 40 kDa. Spin coupling analysis of(approximately) symmetric monomer units is facilitated by using the natural abundance C-13 enrichment to break the local symmetry.

引用

页码：3569 / 3576

页数：8