Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm

被引:0
作者
Osmanov, Yu. I. [1 ,2 ]
Kogan, E. A. [1 ]
Severgina, L. O. [1 ]
Rapoport, L. M. [3 ]
Aleksandrov, N. S. [1 ]
Tsarichenko, D. G. [3 ]
Korolyov, D. O. [3 ]
机构
[1] Sechenov First Moscow State Med Univ, Minist Hlth Russia, Anat Pathol Dept, Build 2,8 Trubetskaya St, Moscow 119991, Russia
[2] Russian Railway, Sci Clin Ctr, Dept Pathol, 84 Volokolamskoe Shosse, Moscow 125367, Russia
[3] Sechenov First Moscow State Med Univ, Minist Hlth Russia, Inst Urol & Reprod Hlth, Build 1,2 Bolshaya Pirogovskaya St, Moscow 119435, Russia
来源
ONKOUROLOGIYA | 2019年 / 15卷 / 03期
关键词
renal cell carcinoma; renal tumors; immunohistochemical diagnosis; IMMUNOHISTOCHEMICAL ANALYSIS; DIFFERENTIAL-DIAGNOSIS; STROMAL TUMOR; CARCINOMA; NEOPLASMS; KIDNEY; GENE; ANGIOMYOLIPOMA; ONCOCYTOMA; CLASSIFICATION;
D O I
10.17650/1726-9776-2019-15-3-126-131
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In the structure of ontological morbidity, renal cell carcinoma takes the 10th place among malignant neoplasms. The increase in incidence is observed from the age of 35-40 years and reaches a maximum at the age of 65-70 years. In terms of frequency of occurrence, clear cell renal cell carcinoma is ranked first among all kidney tumors. Meanwhile, due to the high heterogeneity of renal cell carcinomas with clear cytoplasm group, significant differential diagnostic difficulties arise in the morphological verification of these tumors. The article presents all nasological forms of kidney tumors with clear cytoplasm and provides a database of already known immunohistochemical markers for each nosological unit.
引用
收藏
页码:126 / 131
页数:6
相关论文
共 56 条
[1]   Chromophobe renal cell carcinoma: a comparative study of histological, immunohistochemical and ultrastructural features using high throughput tissue microarray [J].
Abrahams, NA ;
MacLennan, GT ;
Khoury, JD ;
Ormsby, AH ;
Tamboli, P ;
Doglioni, C ;
Schumacher, B ;
Tickoo, SK .
HISTOPATHOLOGY, 2004, 45 (06) :593-602
[2]   Role of Immunohistochemistry in the Evaluation of Needle Core Biopsies in Adult Renal Cortical Tumors: An Ex Vivo Study [J].
Al-Ahmadie, Hikmat A. ;
Alden, Darym ;
Fine, Samson W. ;
Gopalan, Anuradha ;
Touijer, Karim A. ;
Russo, Paul ;
Reuter, Victor E. ;
Tickoo, Satish K. .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2011, 35 (07) :949-961
[3]   Chromophobe Renal Cell Carcinoma: Histomorphologic Characteristics and Evaluation of Conventional Pathologic Prognostic Parameters in 145 Cases [J].
Amin, Mahul B. ;
Paner, Gladell P. ;
Alvarado-Cabrero, Isabel ;
Young, Andrew N. ;
Stricker, Hans J. ;
Lyles, Robert H. ;
Moch, Holger .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2008, 32 (12) :1822-1834
[4]   Prognostic impact of histologic Subtyping of adult renal epithelial neoplasms - An experience of 405 cases [J].
Amin, MB ;
Amin, MB ;
Tamboli, P ;
Javidan, J ;
Stricker, H ;
Venturina, MD ;
Deshpande, A ;
Menon, M .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2002, 26 (03) :281-291
[5]   Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions -: A sensitive and specific immunohistochemical assay [J].
Argani, P ;
Lal, P ;
Hutchinson, B ;
Lui, MY ;
Reuter, VE ;
Ladanyi, M .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2003, 27 (06) :750-761
[6]   Primary renal neoplasms with the ASPL-TFE3 gene fusion of alveolar soft part sarcoma -: A distinctive tumor entity previously included among renal cell carcinomas of children and adolescents [J].
Argani, P ;
Antonescu, CR ;
Illei, PB ;
Lui, MY ;
Timmons, CF ;
Newbury, R ;
Reuter, VE ;
Garvin, AJ ;
Perez-Atayde, AR ;
Fletcher, JA ;
Beckwith, JB ;
Bridge, JA ;
Ladanyi, M .
AMERICAN JOURNAL OF PATHOLOGY, 2001, 159 (01) :179-192
[7]   Xp11 translocation renal cell carcinoma in adults: Expanded clinical, pathologic, and genetic spectrum [J].
Argani, Pedram ;
Olgac, Semra ;
Tickoo, Satish K. ;
Goldfischer, Michael ;
Moch, Holger ;
Chan, David Y. ;
Eble, John N. ;
Bonsib, Stephen M. ;
Jimeno, Mireya ;
Lloreta, Josep ;
Billis, Athanase ;
Hicks, Jessica ;
De Marzo, Angelo M. ;
Reuter, Victor E. ;
Ladanyi, Marc .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2007, 31 (08) :1149-1160
[8]   Renal Cell Carcinoma and Mimics: Pathologic Primer for Radiologists [J].
Bai, Xiaoyan ;
Wu, Chin-Lee .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2012, 198 (06) :1289-1293
[9]  
Banerjee Indraneel, 2016, Rev Urol, V18, P118, DOI 10.3909/riu0692
[10]  
BRUNELLI M, 2010, MODERN PATHOL, V23, pA18