Generation of phosphorus-centered radicals via homolytic substitution at sulfur

被引：79

作者：

Carta, Paola ^{[1
]}

Puljic, Nicolas ^{[1
]}

Robert, Carine ^{[1
]}

Dhimane, Anne-Lise ^{[1
]}

Fensterbank, Louis ^{[1
]}

Lacote, Emmanuel ^{[1
]}

Malacria, Max ^{[1
]}

机构：

[1] Univ Paris 06, Chim Organ Lab, UMR 7611, CNRS,Inst Chim Mol FR 2769, F-75005 Paris, France

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 06期

关键词：

D O I：

10.1021/ol0631096

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel radical domino process relying on the homolytic cleavage of P-S bonds allows the preparation of phosphorus-containing molecules through addition of P-centered radicals onto olefins. The key step of this reaction is a homolytic substitution on a sulfur atom. The scope of the reaction is broad. Diaminophosphonyl radicals whose reactivity was unknown react smoothly with olefins. Use of tin hydride can be avoided. A radical thiophosphinoylation of triple bonds has been uncovered.

引用

页码：1061 / 1063

页数：3

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