A rapid decline in corneal small fibers and occurrence of foot ulceration and Charcot foot

被引：17

作者：

Dehghani, Cirous ^{[1
]}

Russell, Anthony W. ^{[2
,3
]}

Perkins, Bruce A. ^{[4
]}

Malik, Rayaz A. ^{[5
,6
]}

Pritchard, Nicola ^{[1
]}

Edwards, Katie ^{[1
]}

Shahidi, Ayda M. ^{[7
]}

Srinivasan, Sangeetha ^{[1
]}

Efron, Nathan ^{[1
]}

机构：

[1] Queensland Univ Technol, Inst Hlth & Biomed Innovat, 60 Musk Ave, Kelvin Grove, Qld 4059, Australia

[2] Princess Alexandra Hosp, Woolloongabba, Qld, Australia

[3] Univ Queensland, Sch Med, Woolloongabba, Qld, Australia

[4] Univ Toronto, Dept Med, Div Endocrinol & Metab, Toronto, ON, Canada

[5] Univ Manchester, Inst Human Dev, Ctr Endocrinol & Diabet, Manchester, Lancs, England

[6] Weill Cornell Med Coll Qatar, Doha, Qatar

[7] Annidis Corp, Ottawa, ON, Canada

来源：

JOURNAL OF DIABETES AND ITS COMPLICATIONS | 2016年 / 30卷 / 08期

基金：

英国医学研究理事会;

关键词：

Diabetic peripheral neuropathy; Corneal confocal microscopy; Corneal nerve morphology; Diabetic foot complications; Neuropathy measures; CONFOCAL MICROSCOPY; NEUROPATHY; DIAGNOSIS;

D O I：

10.1016/j.jdiacomp.2016.07.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present clinical, neuropathy and corneal nerve morphology data in a participant with type 2 diabetes who developed diabetic foot ulceration, partial amputation and Charcot during a longitudinal observational study. While conventional measures of neuropathy did not deteriorate significantly, corneal nerve parameters showed a rapid reduction prior to the development of foot complications. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：1437 / 1439

页数：3

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