Norovirus genetic diversity and evolution: implications for antiviral therapy

被引：14

作者：

Rocha-Pereira, Joana ^{[1
]}

Van Dycke, Jana ^{[1
]}

Neyts, Johan ^{[1
]}

机构：

[1] Univ Leuven, KU Leuven, Dept Microbiol & Immunol, Rega Inst Med Res,Lab Virol & Chemotherapy, Leuven, Belgium

来源：

CURRENT OPINION IN VIROLOGY | 2016年 / 20卷

关键词：

NUCLEOSIDE ANALOG 2'-C-METHYLCYTIDINE; VIRAL POLYMERASE INHIBITOR; DEPENDENT RNA-POLYMERASES; NORWALK VIRUS; TRANSPLANT RECIPIENTS; MOUSE MODEL; HUMAN-POPULATIONS; INFECTION; GASTROENTERITIS; RECOMBINATION;

D O I：

10.1016/j.coviro.2016.09.009

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human noroviruses are the leading cause of foodborne illness causing both acute and chronic gastroenteritis. In recent years, a number of vaccine candidates entered (pre-) clinical development and the first efforts to develop antiviral therapy have been made. We here discuss aspects of norovirus genetic evolution, persistence in immunocompromised patients as well as the risk and potential consequences of resistance development toward future antiviral drugs.

引用

页码：92 / 98

页数：7

共 75 条

[1] Antibody Responses to Norovirus Genogroup GI.1 and GII.4 Proteases in Volunteers Administered Norwalk Virus [J].

Ajami, Nadim J. ;

Barry, Meagan A. ;

Carrillo, Berenice ;

Muhaxhiri, Zana ;

Neill, Frederick H. ;

Prasad, B. V. Venkataram ;

Opekun, Antone R. ;

Gilger, Mark A. ;

Graham, David Y. ;

Atmar, Robert L. ;

Estes, Mary K. .

CLINICAL AND VACCINE IMMUNOLOGY, 2012, 19 (12) :1980-1983

[2] Norovirus in Transplantation [J].

Angarone, Michael P. ;

Sheahan, Anna ;

Kamboj, Mini .

CURRENT INFECTIOUS DISEASE REPORTS, 2016, 18 (06)

[3]

[Anonymous], EURO SURVEILL

[4] Global Economic Burden of Norovirus Gastroenteritis [J].

Bartsch, Sarah M. ;

Lopman, Benjamin A. ;

Ozawa, Sachiko ;

Hall, Aron J. ;

Lee, Bruce Y. .

PLOS ONE, 2016, 11 (04)

[5] Norovirus Vaccine Against Experimental Human GII.4 Virus Illness: A Challenge Study in Healthy Adults [J].

Bernstein, David I. ;

Atmar, Robert L. ;

Lyon, G. Marshall ;

Treanor, John J. ;

Chen, Wilbur H. ;

Jiang, Xi ;

Vinje, Jan ;

Gregoricus, Nicole ;

Frenck, Robert W., Jr. ;

Moe, Christine L. ;

Al-Ibrahim, Mohamed S. ;

Barrett, Jill ;

Ferreira, Jennifer ;

Estes, Mary K. ;

Graham, David Y. ;

Goodwin, Robert ;

Borkowski, Astrid ;

Clemens, Ralf ;

Mendelman, Paul M. .

JOURNAL OF INFECTIOUS DISEASES, 2015, 211 (06) :870-878

[6] Norovirus Gastroenteritis in Immunocompromised Patients [J].

Bok, Karin ;

Green, Kim Y. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (22) :2126-2132

[7] Chimpanzees as an animal model for human norovirus infection and vaccine development [J].

Bok, Karin ;

Parra, Gabriel I. ;

Mitra, Tanaji ;

Abente, Eugenio ;

Shaver, Charlene K. ;

Boon, Denali ;

Engle, Ronald ;

Yu, Claro ;

Kapikian, Albert Z. ;

Sosnovtsev, Stanislav V. ;

Purcell, Robert H. ;

Green, Kim Y. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (01) :325-330

[8] Norovirus Infections Occur in B-Cell-Deficient Patients [J].

Brown, Julianne R. ;

Gilmour, Kimberly ;

Breuer, Judith .

CLINICAL INFECTIOUS DISEASES, 2016, 62 (09) :1136-1138

[9]

Bull RA, 2005, EMERG INFECT DIS, V11, P1079

[10] Contribution of Intra- and Interhost Dynamics to Norovirus Evolution [J].

Bull, Rowena A. ;

Eden, John-Sebastian ;

Luciani, Fabio ;

McElroy, Kerensa ;

Rawlinson, William D. ;

White, Peter A. .

JOURNAL OF VIROLOGY, 2012, 86 (06) :3219-3229

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