Metaproteomics: Harnessing the Power of High Performance Mass Spectrometry to Identify the Suite of Proteins That Control Metabolic Activities in Microbial Communities

被引：121

作者：

Hettich, Robert L. ^{[1
]}

Pan, Chongle ^{[1
]}

Chourey, Karuna ^{[1
]}

Giannone, Richard J. ^{[1
]}

机构：

[1] Oak Ridge Natl Lab, Oak Ridge, TN 37831 USA

来源：

ANALYTICAL CHEMISTRY | 2013年 / 85卷 / 09期

基金：

美国国家卫生研究院;

关键词：

SHEWANELLA-ONEIDENSIS MR-1; TOP-DOWN; GEL-ELECTROPHORESIS; SHOTGUN PROTEOMICS; IDENTIFICATION TECHNOLOGY; ENVIRONMENTAL PROTEOMICS; PEPTIDE-IDENTIFICATION; SOIL METAPROTEOMICS; BACTERIAL PHYLA; INTACT PROTEINS;

D O I：

10.1021/ac303053e

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The availability of extensive genome information for many different microbes, including unculturable species in mixed communities from environmental samples, has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. To this end, metaproteomics exploits the power of high-performance mass spectrometry for extensive characterization of the complete suite of proteins expressed by a microbial community in an environmental sample.

引用

页码：4203 / 4214

页数：12

共 103 条

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