Preparation of 3-alkyl-4-hydroxy-2-butenyl acetate through highly regioselective lipase-catalyzed hydrolysis of corresponding diacetates

被引：13

作者：

Itoh, T ^{[1
]}

Uzu, A ^{[1
]}

Kanda, N ^{[1
]}

Takagi, Y ^{[1
]}

机构：

[1] HYOGO UNIV EDUC,DEPT CHEM,YASHIRO,HYOGO 67314,JAPAN

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 01期

关键词：

D O I：

10.1016/0040-4039(95)02111-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly regioselective hydrolysis of diacetate of (E)-2-substituted-2-butene-1,4-diol has been demonstrated. Lipase AL (Meito) was chosen from among commercial enzymes as the one most able to preferentially hydrolyze; the acetyl group at 1-position giving monoacetate.

引用

页码：91 / 92

页数：2

共 6 条

[1] REGIOSELECTIVE ENZYME-MEDIATED ACYLATION OF POLYHYDROXY NATURAL COMPOUNDS - A REMARKABLE, HIGHLY EFFICIENT PREPARATION OF 6'-O-ACETYL AND 6'-O-CARBOXYACETYL GINSENOSIDE-RG1 [J].