The economic value of a quadrivalent versus trivalent influenza vaccine

被引：67

作者：

Lee, Bruce Y. ^{[1
,2
]}

Bartsch, Sarah M. ^{[1
,2
]}

Willig, Alyssa M. ^{[1
,2
]}

机构：

[1] Univ Pittsburgh, Sch Med, Publ Hlth Computat & Operat Res PHICOR, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15213 USA

来源：

VACCINE | 2012年 / 30卷 / 52期

关键词：

Influenza; Quadrivalent vaccine; Trivalent vaccine; Economics; SEASONAL INFLUENZA; IMPACT;

D O I：

10.1016/j.vaccine.2012.10.025

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The recently licensed quadrivalent seasonal influenza vaccine (QIV) may provide better protection than the traditional trivalent influenza vaccine (TIV) as it includes one more influenza B strain. We developed a Monte Carlo simulation model to determine the economic value of a QIV compared to the TIV for 10 influenza seasons (1999-2009). The addition of the influenza B strain to convert the TIV into a QIV could result in substantial cost-savings to society (median of $3.1 billion) and third party payers (median of $292 million), even when the cost of QIV is significantly higher. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：7443 / 7446

页数：4

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