Light-Triggered Charge Reversal of Organic-Silica Hybrid Nanoparticles

被引：39

作者：

Hu, Li-Chih ^{[1
]}

Yonamine, Yusuke ^{[1
]}

Lee, Shih-Hui ^{[1
]}

van der Veer, Wytze E. ^{[1
]}

Shea, Kenneth J. ^{[1
]}

机构：

[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 27期

关键词：

BRIDGED POLYSILSESQUIOXANE NANOPARTICLES; GOLD NANOPARTICLES; DRUG-DELIVERY; IN-VIVO; LAYER; NANOSTRUCTURES; FABRICATION; RELEASE; SPHERES;

D O I：

10.1021/ja303118w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A functional nanoparticle with light-triggered charge reversal based on a protected amine-bridged polysilsesquioxane was designed. An emulsion- and amine-free sol gel synthesis was developed to prepare uniform nanospheres. Photolysis of suspensions of these nanoparticles results in a reversal of the zeta potential. This behavior has been used to trigger nanoparticle self-assembly, nanocomposite hydrogel formation, and nanoparticle release, showing the potential of this material in nanoscale manipulation and nanoparticle therapy.

引用

收藏

页码：11072 / 11075

页数：4

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