Testing long-term memory in animal models of schizophrenia: Suggestions from CNTRICS

被引:19
作者
Bussey, Timothy J. [1 ,2 ,3 ]
Barch, Deanna M. [4 ]
Baxter, Mark G. [5 ,6 ]
机构
[1] Univ Cambridge, Dept Expt Psychol, Cambridge CB2 3E8, England
[2] Univ Cambridge, MRC, Cambridge CB2 3E8, England
[3] Univ Cambridge, Wellcome Trust Behav & Clin Neurosci Inst, Cambridge CB2 3E8, England
[4] Washington Univ, Dept Psychol, St Louis, MO 63130 USA
[5] Icahn Sch Med Mt Sinai, Glickenhaus Lab Neuropsychol, New York, NY USA
[6] Icahn Sch Med Mt Sinai, Friedman Brain Inst, Dept Neurosci, New York, NY USA
关键词
Episodic memory; Hippocampus; Mouse; Object recognition; Neuropsychiatric disease; Prefrontal cortex; Rat; Relational memory; Rodent; Paired-associate learning; Touchscreen; EPISODIC-LIKE MEMORY; OBJECT RECOGNITION MEMORY; PERIRHINAL CORTEX; PREFRONTAL CORTEX; HIPPOCAMPAL-LESIONS; TRANSITIVE INFERENCE; TEMPORAL-ORDER; STRATEGY IMPLEMENTATION; ASSOCIATIVE RECOGNITION; COGNITIVE NEUROSCIENCE;
D O I
10.1016/j.neubiorev.2013.06.005
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
This paper reports the results of discussions at the fourth meeting of Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) meeting, held over two days in Washington, DC in April 2011. The meeting focused on animal paradigms for assessing the cognitive constructs relevant to schizophrenia identified in previous CNTRICS meetings. This report focuses on the outcome of discussions in the general area of long-term memory. A number of candidate animal paradigms were discussed. Two of these - one for rodents and one for non-human primates - were recommended as particularly promising for further development. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2141 / 2148
页数:8
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