Changes in NAD Content Induced by Nicotinic Acid-Related Compounds in K562 Cells during Differentiation

被引：0
作者：
Ida, Chieri [1 ]
Ogata, Shin [2 ]
机构：
[1] Nagahama Inst Biosci & Technol, Dept Biosci, Nagahama, Shiga 5260829, Japan
[2] Mie Univ, Grad Sch Bioresources, Mol & Cellular Biol Lab, Tsu, Mie 5148507, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2013年 / 77卷 / 07期
关键词：
nicotinamide adenine dinucleotide (NAD); nicotinic acid; isonicotinic acid; cell differentiation; K562; INDUCTION; LINE; HEMOGLOBIN; BUTYRATE; HEMIN;
D O I：
10.1271/bbb.130131
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two nicotinic acid-related compounds were found to induce erythroid differentiation in K562 cells. We investigated the changes in nicotinamide adenine dinucleotide (NAD) content induced by nicotinic acid-related compounds during differentiation. The NAD content was reduced by a treatment with nicotinic acid and isonicotinic acid. These results provide important clues toward elucidating the erythroid differentiation mechanism.
引用
收藏
页码：1583 / 1585
页数：3
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