Gene delivery platforms

被引：10

作者：

Kim, Jong-Myung ^{[1
,2
]}

Shin, Eunkyoung ^{[2
]}

Ryou, Sang-Mi ^{[2
]}

Yeom, Ji-Hyun ^{[2
]}

Lee, Kangseok ^{[2
]}

机构：

[1] JM ENB, Life & Environm Res Ctr, Gwangmyung 423795, South Korea

[2] Chung Ang Univ, Dept Life Sci, Seoul 156756, South Korea

来源：

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | 2013年 / 18卷 / 04期

关键词：

gene delivery system; GDS; nanoparticle; viral GDS; non-viral GDS; RECOMBINANT ADENOASSOCIATED VIRUS; SMALL INTERFERING RNA; LOW-MOLECULAR-WEIGHT; IN-VIVO; GOLD NANOPARTICLES; SIRNA DELIVERY; TRANSFECTION EFFICIENCY; TARGETED DELIVERY; CELLULAR UPTAKE; PLASMID DNA;

D O I：

10.1007/s12257-012-0546-8

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

One of the key challenges in the experimental and therapeutic use of gene delivery agents is the development of methods that can efficiently deliver nucleic acids into living systems. During the past decade, the development of effective and safe gene delivery systems has been intensively investigated. This review summarizes the current state of gene delivery methods based on viral and non-viral agents.

引用

页码：637 / 647

页数：11

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