Lysosome-related organelles: unusual compartments become mainstream

被引：211

作者：

Marks, Michael S. ^{[1
,2
]}

Heijnen, Harry F. G. ^{[3
,4
,5
]}

Raposo, Graca ^{[6
,7
]}

机构：

[1] Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Dept Physiol, Philadelphia, PA 19104 USA

[3] Lab Clin Chem & Haematol, NL-3584 CX Utrecht, Netherlands

[4] Univ Med Ctr Utrecht, Dept Cell Biol, Cell Microscopy Ctr, NL-3584 CX Utrecht, Netherlands

[5] INSERM, UMR 949, EFS Alsace, F-67065 Strasbourg, France

[6] Inst Curie, Ctr Rech, F-75248 Paris 05, France

[7] CNRS, Unite Mixte Rech 144, F-75248 Paris 05, France

来源：

CURRENT OPINION IN CELL BIOLOGY | 2013年 / 25卷 / 04期

基金：

美国国家卫生研究院;

关键词：

HERMANSKY-PUDLAK-SYNDROME; WEIBEL-PALADE BODIES; SUSCEPTIBILITY FACTOR DYSBINDIN; NUCLEOTIDE EXCHANGE FACTOR; DENSE GRANULE BIOGENESIS; VON-WILLEBRAND-FACTOR; EARLY ENDOSOMES; IMMUNOLOGICAL SYNAPSE; ELECTRON TOMOGRAPHY; SECRETORY LYSOSOMES;

D O I：

10.1016/j.ceb.2013.04.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Lysosome-related organelles (LROs) comprise a group of cell type-specific subcellular compartments with unique composition, morphology and structure that share some features with endosomes and lysosomes and that function in varied processes such as pigmentation, hemostasis, lung plasticity and immunity. In recent years, studies of genetic diseases in which LRO functions are compromised have provided new insights into the mechanisms of LRO biogenesis and the regulated secretion of LRO contents. These insights have revealed previously unappreciated specialized endosomal sorting processes in all cell types, and are expanding our views of the plasticity of the endosomal and secretory systems in adapting to cell type-specific needs.

引用

页码：495 / 505

页数：11

共 99 条

[11] Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth [J].

Burgo, Andrea ;

Sotirakis, Emmanuel ;

Simmler, Marie-Christine ;

Verraes, Agathe ;

Chamot, Christophe ;

Simpson, Jeremy C. ;

Lanzetti, Letizia ;

Proux-Gillardeaux, Veronique ;

Galli, Thierry .

EMBO REPORTS, 2009, 10 (10) :1117-1124

[12] The clathrin adaptor complex AP-1 binds HIV-1 and MLV Gag and facilitates their budding [J].

Camus, Gregory ;

Segura-Morales, Carolina ;

Molle, Dorothee ;

Lopez-Verges, Sandra ;

Begon-Pescia, Christina ;

Cazevieille, Chantal ;

Schu, Peter ;

Bertrand, Edouard ;

Berlioz-Torrent, Clarisse ;

Basyuk, Eugenia .

MOLECULAR BIOLOGY OF THE CELL, 2007, 18 (08) :3193-3203

[13] A LYST/beige homolog is involved in biogenesis of Dictyostelium secretory lysosomes [J].

Charette, Steve J. ;

Cosson, Pierre .

JOURNAL OF CELL SCIENCE, 2007, 120 (14) :2338-2343

[14] Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells [J].

Cote, Marjorie ;

Menager, Mickael M. ;

Burgess, Agathe ;

Mahlaoui, Nizar ;

Picard, Capucine ;

Schaffner, Catherine ;

Al-Manjomi, Fahad ;

Al-Harbi, Musa ;

Alangari, Abdullah ;

Le Deist, Francoise ;

Gennery, Andrew R. ;

Prince, Nathalie ;

Cariou, Astrid ;

Nitschke, Patrick ;

Blank, Ulrich ;

El-Ghazali, Gehad ;

Menasche, Gael ;

Latour, Sylvain ;

Fischer, Alain ;

de Saint Basile, Genevieve .

JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (12) :3765-3773

[15] RETRACTED: A BLOC-1 Mutation Screen Reveals that PLDN Is Mutated in Hermansky-Pudlak Syndrome Type 9 (Retracted article. See vol. 100, pg. 837, 2017) [J].

Cullinane, Andrew R. ;

Curry, James A. ;

Carmona-Rivera, Carmelo ;

Summers, C. Gail ;

Ciccone, Carla ;

Cardillo, Nicholas D. ;

Dorward, Heidi ;

Hess, Richard A. ;

White, James G. ;

Adams, David ;

Huizing, Marjan ;

Gahl, William A. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2011, 88 (06) :778-787

[16] Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization [J].

Cullinane, Andrew R. ;

Straatman-Iwanowska, Anna ;

Zaucker, Andreas ;

Wakabayashi, Yoshiyuki ;

Bruce, Christopher K. ;

Luo, Guanmei ;

Rahman, Fatimah ;

Gurakan, Figen ;

Utine, Eda ;

Ozkan, Tanju B. ;

Denecke, Jonas ;

Vukovic, Jurica ;

Di Rocco, Maja ;

Mandel, Hanna ;

Cangul, Hakan ;

Matthews, Randolph P. ;

Thomas, Steve G. ;

Rappoport, Joshua Z. ;

Arias, Irwin M. ;

Wolburg, Hartwig ;

Knisely, A. S. ;

Kelly, Deirdre A. ;

Mueller, Ferenc ;

Maher, Eamonn R. ;

Gissen, Paul .

NATURE GENETICS, 2010, 42 (04) :303-U55

[17] Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules [J].

Dabrazhynetskaya, Alena ;

Ma, Jinxia ;

Guerreiro-Cacais, Andre Ortlieb ;

Arany, Zita ;

Rudd, Eva ;

Henter, Jan-Inge ;

Karre, Klas ;

Levitskaya, Jelena ;

Levitsky, Victor .

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2012, 16 (01) :129-141

[18] AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis [J].

Delevoye, Cedric ;

Hurbain, Ilse ;

Tenza, Daniele ;

Sibarita, Jean-Baptiste ;

Uzan-Gafsou, Stephanie ;

Ohno, Hiroshi ;

Geerts, Willie J. C. ;

Verkleij, Arie J. ;

Salamero, Jean ;

Marks, Michael S. ;

Raposo, Graca .

JOURNAL OF CELL BIOLOGY, 2009, 187 (02) :247-264

[19] AP-3-dependent trafficking and disease: the first decade [J].

Dell'Angelica, Esteban C. .

CURRENT OPINION IN CELL BIOLOGY, 2009, 21 (04) :552-559

[20] BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes [J].

Di Pietro, Santiago M. ;

Falcon-Perez, Juan M. ;

Tenza, Daniele ;

Setty, Subba R. G. ;

Marks, Michael S. ;

Raposo, Graca ;

Dell'Angelica, Esteban C. .

MOLECULAR BIOLOGY OF THE CELL, 2006, 17 (09) :4027-4038

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