Spin-echo planar spectroscopic imaging for fast lipid characterization in bone marrow

被引：8

作者：

Bao, S ^{[1
]}

Guttmann, CGR ^{[1
]}

Mugler, JP ^{[1
]}

Brookeman, JR ^{[1
]}

Panych, LP ^{[1
]}

Kraft, RA ^{[1
]}

Oshio, K ^{[1
]}

Jaramillo, D ^{[1
]}

Jolesz, FA ^{[1
]}

Williamson, DS ^{[1
]}

Mulkern, RV ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Childrens Hosp, Dept Radiol, Boston, MA 02115 USA

来源：

MAGNETIC RESONANCE IMAGING | 1999年 / 17卷 / 08期

关键词：

lipids; H-1; MRS; echo planar imaging (EPI);

D O I：

10.1016/S0730-725X(99)00056-9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Lipid characterization of bone marrow in vivo with proton magnetic resonance spectroscopy was performed using Spin-Echo Planar Spectroscopic Imaging sequences. The methods are shown capable of rapidly generating two-dimensional chemical shift imaging data sets suitable for measuring lipid indices that reflect unsaturation levels among triglycerides, as demonstrated in oil phantoms and bone marrow from a healthy volunteer. The volume coverage, spatial resolution, acquisition speed; and spectral characteristics of Spin-Echo Planar Spectroscopic Imaging should make it attractive for clinical studies of diseases affecting normal lipid chemical composition. (C) 1999 Elsevier Science Inc.

引用

页码：1203 / 1210

页数：8

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