Physical activity attenuates the negative effect of low birth weight on leptin levels in European adolescents; The HELENA study

被引：12

作者：

Labayen, I. ^{[1
,2
]}

Ortega, F. B. ^{[3
,4
]}

Moreno, L. A. ^{[2
,5
]}

Gonzalez-Gross, M. ^{[6
,7
]}

Jimenez-Pavon, D. ^{[2
,4
]}

Martinez-Gomez, D. ^{[8
]}

Breidenassel, C. ^{[7
]}

Marcos, A. ^{[8
]}

Molnar, D. ^{[9
]}

Manios, Y. ^{[10
]}

Plada, M. ^{[11
]}

Kafatos, A. ^{[11
]}

De Henauw, S. ^{[12
]}

Mauro, B. ^{[13
]}

Zaccaria, M. ^{[13
]}

Widhalm, K. ^{[14
]}

Gottrand, F. ^{[15
]}

Castillo, M. J. ^{[4
]}

Sjostrom, M. ^{[3
]}

Ruiz, J. R. ^{[3
,16
]}

机构：

[1] Univ Basque Country, Dept Nutr & Food Sci, Vitoria, Spain

[2] GENUD Growth Exercise Nutr & Dev Res Grp, Zaragoza, Spain

[3] Karolinska Inst, Dept Biosci & Nutr NOVUM, Unit Prevent Nutr, Huddinge, Sweden

[4] Univ Granada, Sch Med, Dept Med Physiol, Granada, Spain

[5] Univ Zaragoza, Sch Hlth Sci, Zaragoza, Spain

[6] Univ Politecn Madrid, Fac Phys Act & Sport Sci INEF, Dept Hlth & Human Performance, E-28040 Madrid, Spain

[7] Univ Bonn, Inst Ernahrungs & Lebensmittelwissensch Humanerna, Bonn, Germany

[8] Spanish Natl Res Council, Inst Food Sci Technol & Nutr, Dept Metab & Nutr, Immunonutr Res Grp, Madrid, Spain

[9] Univ Pecs, Dept Pediat, H-7623 Pecs, Hungary

[10] Harokopio Univ, Dept Nutr & Dietet, Athens, Greece

[11] Univ Crete, Sch Med, Prevent Med & Nutr Unit, Iraklion, Crete, Greece

[12] Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium

[13] INRAN Natl Res Inst Food & Nutr, Rome, Italy

[14] Med Univ Vienna, Div Clin Nutr, Dept Pediat, Vienna, Austria

[15] Univ Lille, Fac Med, INSERM, U995, Lille, France

[16] Univ Granada, Sch Sport Sci, Dept Phys Educ & Sport, Granada, Spain

来源：

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | 2013年 / 23卷 / 04期

关键词：

Physical activity; Birth weight; Leptin; Adolescents; Insulin; CHILDREN; YOUTH; ASSOCIATION; NUTRITION; GROWTH; FAT;

D O I：

10.1016/j.numecd.2011.12.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We examined whether physical activity (PA) influences the association between birth weight and serum leptin in adolescents. The study comprised a total of 538 adolescents (315 girls), aged 12.5-17.49 years, born at term (>= 37 weeks of gestation). We measured serum leptin levels and time engaged in moderate-vigorous PA (MVPA) by accelerometry. There was an interaction effect between birth weight and meeting the PA recommendations (60 min/day MVPA) on leptin levels in girls (P = 0.023) but not in boys (P = 0.809). Birth weight was negatively associated with leptin levels in girls not meeting the PA recommendations (i.e. more than 60 min/day of MVPA) (beta = -0.096, P = 0.009), whereas no significant association was observed in those meeting the PA recommendations (beta = -0.061, P = 0.433). In conclusion, meeting the PA recommendations may attenuate the negative effect of low birth weight on serum leptin levels in European female adolescents. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：344 / 349

页数：6

共 24 条

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