Current Perspectives of Anticoagulation in Patients With COVID-19

被引:17
作者
Gavioli, Elizabeth M. [1 ]
Sikorska, Gabriela [1 ]
Man, Ammy [1 ]
Rana, Jay [1 ]
Vider, Etty [1 ,2 ]
机构
[1] Arnold & Marie Schwartz Coll Pharm & Hlth Sci, Div Pharm, Brooklyn, NY USA
[2] Brookdale Hosp, Med Ctr, Div Pharm, Brooklyn, NY USA
关键词
SARS-CoV-2; COVID-19; thromboembolism; anticoagulation; MANAGEMENT; DISEASE;
D O I
10.1097/FJC.0000000000000861
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thromboembolism and myocardial injury is common in patients with COVID-19. Low-molecular-weight heparin appears to be associated with a good prognosis in patients with COVID-19 and has the ability to reduce coagulation and inflammation markers. Hospitalized patients with COVID-19 should be placed on thromboprophylaxis with the option of full therapeutic anticoagulation or tissue plasminogen activator in high-risk or mechanically ventilated patients. Thromboprophylaxis should also be considered at hospital discharge for high-risk patients. Clinical judgment should be used to evaluate the bleeding and safety risk of anticoagulation in patients with COVID-19 without confirmed data.
引用
收藏
页码:146 / 150
页数:5
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