New solid-supported reagents (SSRs) for selective acylation of amines

被引：13

作者：

Botta, M ^{[1
]}

Corelli, F ^{[1
]}

Petricci, E ^{[1
]}

Seri, C ^{[1
]}

机构：

[1] Univ Siena, Dipartimento Farm Chim Tecnol, I-53100 Siena, Italy

来源：

HETEROCYCLES | 2002年 / 56卷 / 1-2期

关键词：

D O I：

10.3987/COM-01-S(K)50

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The pyrimidine linker (4) was prepared by solid phase synthesis starting from Merrifield resin. Acylation of 4 with different acyl chlorides gave polymer-bound 4-acyloxypyrimidines (2a-c), which proved to be useful solid-supported reagents for the selective acylation of amines. Their use in solution combinatorial chemistry has been also envisaged.

引用

页码：369 / 377

页数：9

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