New solid-supported reagents (SSRs) for selective acylation of amines

被引：13
|
作者：
Botta, M [1 ]
Corelli, F [1 ]
Petricci, E [1 ]
Seri, C [1 ]
机构：
[1] Univ Siena, Dipartimento Farm Chim Tecnol, I-53100 Siena, Italy
来源：
HETEROCYCLES | 2002年 / 56卷 / 1-2期
关键词：
D O I：
10.3987/COM-01-S(K)50
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The pyrimidine linker (4) was prepared by solid phase synthesis starting from Merrifield resin. Acylation of 4 with different acyl chlorides gave polymer-bound 4-acyloxypyrimidines (2a-c), which proved to be useful solid-supported reagents for the selective acylation of amines. Their use in solution combinatorial chemistry has been also envisaged.
引用
收藏
页码：369 / 377
页数：9
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