Parotid sclerosing mucoepidermoid carcinoma: a case report and immunohistochemical study

被引：0
作者：
Gherghina, Florin-Liviu [1 ]
Camen, Adrian [2 ]
Munteanu, Maria Cristina [2 ]
Margaritescu, Claudu [3 ]
Sarla, Calin-Gabriel [4 ]
机构：
[1] Univ Med & Pharm Craiova, Dept Phys Med & Rehabil, Craiova, Romania
[2] Univ Med & Pharm Craiova, Dept Oral & Maxillofacial Surg, Craiova, Romania
[3] Univ Med & Pharm Craiova, Dept Pathol, Fac Dent, 2 Petru Rares St, Craiova 200349, Romania
[4] Vasile Goldis Western Univ, Dept Phys Educ & Sports, Arad, Romania
来源：
ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY | 2016年 / 57卷 / 03期
关键词：
sclerosing mucoepidermoid carcinoma; immunohistochemistry; parotid gland; tumor grade malignancy; SALIVARY-GLAND TUMORS; GROWTH-FACTOR RECEPTOR; PROGNOSTIC-FACTORS; PROGESTERONE-RECEPTORS; CELL-PROLIFERATION; EXPRESSION; NEOPLASMS; GRADE; POPULATION; ACTIVATION;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Here we report the case of a 63-year-old female with a parotid sderosing mucoepidermoid carcinoma diagnosed and treated at the Department of Oral and Maxillofacial Surgery, Emergency County Hospital of Craiova, Romania. The clinical and imaging investigation revealed a parotid malignant tumor with central fluid-filled cystic formation. Histopathology found an intermediate grade sclerosing mucoepidermoid carcinoma that invaded the adjacent adipose and striated muscle tissues, but without perineural and lymphovascular invasion. The immunohistochemistry investigated mainly biomarkers involved in the induction of a local aggressive behavior. This case report describes a rare parotid sclerosing mucoepidermoid carcinoma with peculiar clinical and morphological characteristic features. The immunohistochemical study sustained its intermediate grade malignancy highlighting the prognostic value of some of the used biomarkers.
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收藏
页码：1107 / 1116
页数：10
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