S-Methyl-(-N-aryl and -N-alkyl)isothioureas derived from 2-aminobenzothiazole

被引：6

作者：

Cruz, Alejandro ^{[1
]}

Padilla-Martinez, Itzia I. ^{[1
]}

Garcia-Baez, Efren V. ^{[1
]}

Juarez Juarez, Minerva ^{[1
]}

机构：

[1] IPN, Unidad Profes Interdisciplinaria Biotecnol, Dept Quim, Av Acueducto S-N, Mexico City 07340, DF, Mexico

来源：

ARKIVOC | 2008年

关键词：

2-Aminobenzothiazole; carbon disulfide; S-methyl group; isothioureas; guanidines; pyrrolidine; piperazine;

D O I：

10.3998/ark.5550190.0009.516

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

S-Methylisothioureas, 2-N-H, -N-alkyl and -N-aryl are synthesized from the reaction of ammonia or the corresponding aromatic amines with benzothiazole dithiomethylcarboimidate. The reaction with pyrrolidine and piperazine are reported. Compounds were characterized by H-1 and C-13 NMR spectroscopy and the X-ray molecular structure of S-methy-N-benzothiazolelisothiourea derivative is reported.

引用

页码：200 / 209

页数：10

共 20 条

[1]

[Anonymous], 1999, J. Appl. Crystallogr, DOI [DOI 10.1107/S0021889899006020, 10.1107/S0021889899006020]

[2] FURTHER ENHANCEMENT OF ANALGESIC ACTIVITY - ENKEPHALIN ANALOGS WITH TERMINAL GUANIDINO GROUP [J].