Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

被引：371

作者：

Ostermann, Marlies ^{[1
]}

Bellomo, Rinaldo ^{[2
]}

Burdmann, Emmanuel A. ^{[3
]}

Doi, Kent ^{[4
]}

Endre, Zoltan H. ^{[5
,6
]}

Goldstein, Stuart L. ^{[7
,8
]}

Kane-Gill, Sandra L. ^{[9
]}

Liu, Kathleen D. ^{[10
,11
]}

Prowle, John R. ^{[12
]}

Shaw, Andrew D. ^{[13
]}

Srisawat, Nattachai ^{[14
,15
,16
,17
,18
]}

Cheung, Michael ^{[19
]}

Jadoul, Michel ^{[20
]}

Winkelmayer, Wolfgang C. ^{[21
]}

Kellum, John A. ^{[22
]}

机构：

[1] Kings Coll London, Guys & St Thomas Hosp, Dept Crit Care, London, England

[2] Univ Melbourne, Ctr Integrated Crit Care, Melbourne, Vic, Australia

[3] Univ Sao Paulo, Sch Med, Lab Invest Med 12, Div Nephrol, Sao Paulo, Brazil

[4] Univ Tokyo, Dept Emergency & Crit Care Med, Tokyo, Japan

[5] Univ New South Wales, Prince Wales Hosp, Randwick, NSW, Australia

[6] Univ New South Wales, Sch Clin, Randwick, NSW, Australia

[7] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

[8] Cincinnati Childrens Hosp, Dept Pediat, Cincinnati, OH USA

[9] Univ Pittsburgh, Sch Pharm, Dept Pharm & Therapeut, Pittsburgh, PA 15261 USA

[10] Univ Calif San Francisco, Dept Med, Div Nephrol, San Francisco, CA 94143 USA

[11] Univ Calif San Francisco, Dept Anesthesia, Div Crit Care Med, San Francisco, CA USA

[12] Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London, England

[13] Univ Alberta, Dept Anesthesiol & Pain Med, Edmonton, AB, Canada

[14] Chulalongkorn Univ, Fac Med, Dept Med, Div Nephrol, Bangkok, Thailand

[15] Chulalongkorn Univ, Fac Med, Crit Care Nephrol Res Unit, Bangkok, Thailand

[16] Chulalongkorn Univ, Trop Med Cluster, Bangkok, Thailand

[17] King Chulalongkorn Mem Hosp, Excellence Ctr Crit Care Nephrol, Bangkok, Thailand

[18] Royal Soc Thailand, Acad Sci, Bangkok, Thailand

[19] Kidney Dis Improving Global Outcomes KDIGO, Brussels, Belgium

[20] Catholic Univ Louvain, Clin Univ St Luc, Brussels, Belgium

[21] Baylor Coll Med, Dept Med, Selzman Inst Kidney Hlth, Nephrol Sect, Houston, TX 77030 USA

[22] Univ Pittsburgh, Sch Med, Dept Crit Care Med, Pittsburgh, PA USA

来源：

KIDNEY INTERNATIONAL | 2020年 / 98卷 / 02期

关键词：

acute kidney disease; acute kidney injury; fluid management; nephrotoxicity; renal replacement therapy; risk stratification; RENAL-REPLACEMENT THERAPY; EXTRACORPOREAL MEMBRANE-OXYGENATION; CRITICALLY-ILL PATIENTS; RESPIRATORY-DISTRESS-SYNDROME; GOAL-DIRECTED RESUSCITATION; FUROSEMIDE STRESS TEST; HEPARIN ANTICOAGULATION; BALANCED CRYSTALLOIDS; HYDROXYETHYL STARCH; PREDICTION MODELS;

D O I：

10.1016/j.kint.2020.04.020

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). The guideline was derived from evidence available through February 2011. Since then, new evidence has emerged that has important implications for clinical practice in diagnosing and managing AKI. In April of 2019, KDIGO held a controversies conference entitled Acute Kidney Injury with the following goals: determine best practices and areas of uncertainty in treating AKI; review key relevant literature published since the 2012 KDIGO AKI guideline; address ongoing controversial issues; identify new topics or issues to be revisited for the next iteration of the KDIGO AKI guideline; and outline research needed to improve AKI management. Here, we present the findings of this conference and describe key areas that future guidelines may address.

引用

页码：294 / 309

页数：16

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