Chitosan/cashew gum nanogels for essential oil encapsulation

被引：154

作者：

Abreu, Flavia O. M. S. ^{[1
]}

Oliveira, Erick F. ^{[1
]}

Paula, Haroldo C. B. ^{[1
]}

de Paula, Regina C. M. ^{[2
]}

机构：

[1] Univ Fed Ceara, Dept Analyt & Phys Chem, UFC, Fortaleza, Ceara, Brazil

[2] Univ Fed Ceara, Dept Organ & Inorgan Chem, UFC, Fortaleza, Ceara, Brazil

来源：

CARBOHYDRATE POLYMERS | 2012年 / 89卷 / 04期

关键词：

Chitosan; Cashew gum; Nanogel; Characterization; Essential oil; NANOPARTICLES; MICROSPHERES; PRESERVATION; ALGINATE; RELEASE;

D O I：

10.1016/j.carbpol.2012.04.048

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Nanogels based on chitosan and cashew gum were prepared and loaded with Lippia sidoides oil. Several parameters such as cashew gum concentration and relative oil content in the matrix had their influence on nanogel properties investigated. Nanogels were characterized regarding their morphologies, particle size distributions, zeta potential, Fourier transform infrared spectroscopy and essential oil contents. The release profile was investigated by UV/vis spectroscopy and its efficacy was determined through bioassays. Results showed that samples designed using relative ratios matrix:oil 10:2, gum:chitosan 1:1 and 5% gum concentration showed high loading (11.8%) and encapsulation efficiency (70%). Nanogels were found to exhibit average sizes in the range 335-558 nm. In vitro release profiles showed that nanoparticles presented slower and sustained release. Bioassays showed that larval mortality was related mainly to oil loading, with samples presenting more effective larvicide efficacies than the pure L. sidoides oil. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1277 / 1282

页数：6

共 29 条

[1] [Anonymous], 1998, POLYM INT
[2] Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications
Berger, J
Reist, M
Mayer, JM
Felt, O
Gurny, R
[J]. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2004, 57 (01) : 35 - 52
[3] Anthelmintic activity of Croton zehntneri and Lippia sidoides essential oils
Camurca-Vasconcelos, A. L. F.
Bevilaqua, C. M. L.
Morais, S. M.
Maciel, M. V.
Costa, C. T. C.
Macedo, I. T. F.
Oliveira, L. M. B.
Braga, R. R.
Silva, R. A.
Vieira, L. S.
[J]. VETERINARY PARASITOLOGY, 2007, 148 (3-4) : 288 - 294
[4] Larvicidal activity of the essential oil from Lippia sidoides Cham. against Aedes aegypti Linn.
Carvalho, AFU
Melo, VMM
Craveiro, AA
Machado, MIL
Bantim, MB
Rabelo, EF
[J]. MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2003, 98 (04): : 569 - 571
[5] Production and characterization of a new dextrin based hydrogel
Carvalho, Joana
Goncalves, Catarina
Gil, Ana M.
Gama, Francisco M.
[J]. EUROPEAN POLYMER JOURNAL, 2007, 43 (07) : 3050 - 3059
[6] Synthesis and characterization of cashew gum/acrylic acid nanoparticles
da Silva, Durcilene A.
Feitosa, Judith P. A.
Paula, Haroldo C. B.
de Paula, Regina C. M.
[J]. MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2009, 29 (02): : 437 - 441
[7] Polymer relationships during preparation of chitosan-alginate and poly-l-lysine-alginate nanospheres
De, SJ
Robinson, D
[J]. JOURNAL OF CONTROLLED RELEASE, 2003, 89 (01) : 101 - 112
[8] Characterization of Lippia sidoides oil extract-β-cyclodextrin complexes using combined thermoanalytical techniques
Fernandes, LP
Éhen, Z
Moura, TF
Novák, C
Sztatisz, J
[J]. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2004, 78 (02) : 557 - 573
[9] Volatile Retention and Antifungal Properties of Spray-Dried Microparticles of Lippia sidoides Essential Oil
Fernandes, Luciana P.
Turatti, Izabel C. C.
Lopes, Norberto P.
Ferreira, Joseane C.
Candido, Regina C.
Oliveira, Wanderley P.
[J]. DRYING TECHNOLOGY, 2008, 26 (12) : 1534 - 1542
[10] Nanoparticles prepared by self-assembly of Chitosan and poly-γ-glutamic acid
Hajdu, Istvan
Bodnar, Magdolna
Filipcsei, Genoveva
Hartmann, John F.
Daroczi, Lajos
Zrinyi, Miklos
Borbely, Janos
[J]. COLLOID AND POLYMER SCIENCE, 2008, 286 (03) : 343 - 350

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