Global Perspectives on Immunization During Pregnancy and Priorities for Future Research and Development: An International Consensus Statement

被引:90
作者
Abu-Raya, Bahaa [1 ]
Maertens, Kirsten [2 ]
Edwards, Kathryn M. [3 ]
Omer, Saad B. [4 ]
Englund, Janet A. [5 ]
Flanagan, Katie L. [6 ,7 ,8 ]
Snape, Matthew D. [9 ]
Amirthalingam, Gayatri [10 ]
Leuridan, Elke [2 ]
Van Damme, Pierre [2 ]
Papaevangelou, Vana [11 ]
Launay, Odile [12 ]
Dagan, Ron [13 ]
Campins, Magda [14 ]
Cavaliere, Anna Franca [15 ]
Frusca, Tiziana [16 ]
Guidi, Sofia [15 ]
O'Ryan, Miguel [17 ]
Heininger, Ulrich [18 ]
Tan, Tina [19 ]
Alsuwaidi, Ahmed R. [20 ]
Safadi, Marco. A. [21 ]
Vilca, Luz M. [22 ]
Wanlapakorn, Nasamon [23 ]
Madhi, Shabir A. [24 ,25 ]
Giles, Michelle L. [26 ]
Prymula, Roman [27 ]
Ladhani, Shamez [10 ]
Martinon-Torres, Federico [28 ]
Tan, Litjen [29 ]
Michelin, Lessandra [30 ]
Scambia, Giovanni [15 ]
Principi, Nicola [31 ]
Esposito, Susanna [32 ]
机构
[1] Univ British Columbia, Dept Pediat, Vancouver, BC, Canada
[2] Univ Antwerp, Vaccine & Infect Dis Inst, Ctr Evaluat Vaccinat, Fac Med & Hlth Sci, Antwerp, Belgium
[3] Vanderbilt Univ, Dept Pediat, Div Pediat Infect Dis, Sch Med, Nashville, TN 37232 USA
[4] Yale Sch Publ Hlth, Yale Sch Med, Dept Internal Med Infect Dis, Dept Epidemiol Microbial Dis, New Haven, CT USA
[5] Univ Washington, Dept Pediat, Seattle Childrens Res Inst, Seattle, WA 98195 USA
[6] Univ Tasmania, Sch Med, Fac Hlth Sci, Launceston, Tas, Australia
[7] RMIT Univ, Sch Hlth & Biomed Sci, Melbourne, Vic, Australia
[8] Monash Univ, Dept Pathol & Immunol, Melbourne, Vic, Australia
[9] Univ Oxford, Dept Paediat, Oxford Vaccine Grp, Oxford, England
[10] Publ Hlth England, Natl Infect Serv, Immunisat & Countermeasures Div, London, England
[11] Natl & Kapodistrian Univ Athens, Univ Hosp ATTIKON, Dept Pediat 3, Athens, Greece
[12] Univ Paris, AP HP, FCRIN I REIVAC, INSERM,CIC 1417, Paris, France
[13] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, Israel
[14] Hosp Univ Vall Hebron, Prevent Med & Epidemiol Dept, Barcelona, Spain
[15] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Salute Donna & Bambino & Sanita, Rome, Italy
[16] Univ Parma, Obstet & Gynaecol Unit, Dept Med & Surg, Parma, Italy
[17] Univ Chile, Millennium Inst Immunol & Immunotherapy, Inst Biomed Sci & Associate Researcher, Microbiol & Mycol Program,Fac Med, Santiago, Chile
[18] Univ Basel, Childrens Hosp, Pediat Infect Dis, Basel, Switzerland
[19] Northwestern Univ, Dept Pediat, Ann & Robert H Lurie Childrens Hosp Chicago, Feinberg Sch Med,Div Pediat Infect Dis, Chicago, IL 60611 USA
[20] United Arab Emirates Univ, Coll Med & Hlth Sci, Dept Pediat, Al Ain, U Arab Emirates
[21] Santa Casa Sao Paulo Sch Med Sci, Dept Pediat, Sao Paulo, Brazil
[22] Univ Milan, Buzzi Hosp ASST Fatebenefratelli Sacco, Unit Obstet & Gynecol, Milan, Italy
[23] Chulalongkorn Univ, Fac Med, Dept Pediat, Ctr Excellence Clin Virol, Bangkok, Thailand
[24] Univ Witwatersrand, Fac Hlth Sci, Natl Res Fdn Vaccine Preventable Dis, Dept Sci & Technol, Johannesburg, South Africa
[25] Univ Witwatersrand, Resp & Meningeal Pathogens Res Unit, Med Res Council, Fac Hlth Sci, Johannesburg, South Africa
[26] Monash Univ, Dept Obstet & Gynaecol, Melbourne, Vic, Australia
[27] Charles Univ Prague, Inst Social Med, Sch Med Hradec Kralove, Prague, Czech Republic
[28] Univ Santiago, Hosp Clin Univ Santiago de Compostela, Translat Pediat & Infect Dis, Dept Pediat, Santiago De Compostela, Spain
[29] Immunizat Act Coalit, St Paul, MN USA
[30] Univ Caixas Do Sul, Hlth Sci Post Grad Program, Infect Dis & Vaccinol Div, Caxias Do Sul, RS, Brazil
[31] Univ Milan, Milan, Italy
[32] Univ Parma, Pietro Barilla Childrens Hosp, Dept Med & Surg, Pediat Clin, Parma, Italy
关键词
group BStreptococcusvaccines; influenza; maternal immunization; pertussis; pregnant women; respiratory syncytial virus; tetanus; RESPIRATORY SYNCYTIAL VIRUS; MATERNAL INFLUENZA IMMUNIZATION; 2009; H1N1; INFLUENZA; TRANSPLACENTAL ANTIBODY TRANSFER; ACELLULAR PERTUSSIS VACCINATION; B STREPTOCOCCAL DISEASE; ADVERSE BIRTH OUTCOMES; SPONTANEOUS-ABORTION; TDAP IMMUNIZATION; IMMUNE-RESPONSE;
D O I
10.3389/fimmu.2020.01282
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Immunization during pregnancy has been recommended in an increasing number of countries. The aim of this strategy is to protect pregnant women and infants from severe infectious disease, morbidity and mortality and is currently limited to tetanus, inactivated influenza, and pertussis-containing vaccines. There have been recent advancements in the development of vaccines designed primarily for use in pregnant women (respiratory syncytial virus and group BStreptococcusvaccines). Although there is increasing evidence to support vaccination in pregnancy, important gaps in knowledge still exist and need to be addressed by future studies. This collaborative consensus paper provides a review of the current literature on immunization during pregnancy and highlights the gaps in knowledge and a consensus of priorities for future research initiatives, in order to optimize protection for both the mother and the infant.
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页数:24
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