Amplified Fluorescence Aptamer-Based Sensors Using Exonuclease III for the Regeneration of the Analyte

被引:113
作者
Liu, Xiaoqing [1 ,2 ]
Freeman, Ronit [1 ,2 ]
Willner, Itamar [1 ,2 ]
机构
[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel
[2] Hebrew Univ Jerusalem, Ctr Nanosci & Nanotechnol, IL-91904 Jerusalem, Israel
关键词
amplification; aptamers; exonuclease; fluorescence; sensors; ROLLING CIRCLE AMPLIFICATION; HEMIN/G-QUADRUPLEXES; PROTEIN-DETECTION; AU NANOPARTICLES; PROTECTION ASSAY; TARGET BINDING; DNA DETECTION; QUANTUM DOTS; COCAINE; THROMBIN;
D O I
10.1002/chem.201103342
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Quick and easy detection: The Exo III-stimulated regeneration of the analyte by the digestion of supramolecular aptamer-analyte complexes provides a means to develop amplified optical aptasensors (see figure). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2207 / 2211
页数:5
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