High resolution detectors based on continuous crystals and SiPMs for small animal PET

被引：27

作者：

Cabello, J. ^{[1
]}

Barrillon, P. ^{[2
]}

Barrio, J. ^{[1
]}

Bisogni, M. G. ^{[3
,4
]}

Del Guerra, A. ^{[3
,4
]}

Lacasta, C. ^{[1
]}

Rafecas, M. ^{[1
,5
]}

Saikouk, H. ^{[6
]}

Solaz, C. ^{[1
]}

Solevi, P. ^{[1
]}

de La Taille, C. ^{[2
]}

Llosa, G. ^{[1
]}

机构：

[1] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain

[2] Lab Accelerateur Lineaire, F-91405 Orsay, France

[3] Univ Pisa, Dipartimento Fis E Fermi, Pisa, Italy

[4] INFN Pisa, Pisa, Italy

[5] Univ Valencia, Dept Fis Atom Nucl & Mol, Valencia, Spain

[6] Univ Mohammed V Agdal, Fac Sci, Lab Phys Nucl, Rabat, Morocco

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2013年 / 718卷

关键词：

Monolithic crystals; SiPM; PET; High resolution; Position determination; DEPTH;

D O I：

10.1016/j.nima.2012.08.094

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Sensitivity and spatial resolution are the two main factors to maximize in emission imaging. The improvement of one factor deteriorates the other with pixelated crystals. In this work we combine SiPM matrices with monolithic crystals, using an accurate gamma-ray interaction position determination algorithm that provides depth of interaction. Continuous crystals provide higher sensitivity than pixelated crystals, while an accurate interaction position determination does not degrade the spatial resolution. Monte Carlo simulations and experimental data show good agreement both demonstrating submillimetre intrinsic spatial resolution. A system consisting in two rotating detectors in coincidence is currently under operation already producing tomographic images. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：148 / 150

页数：3

共 9 条

[1] Maximum-Likelihood Methods for Processing Signals From Gamma-Ray Detectors [J].

Barrett, Harrison H. ;

Hunter, William C. J. ;

Miller, Brian William ;

Moore, Stephen K. ;

Chen, Yichun ;

Furenlid, Lars R. .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2009, 56 (03) :725-735

[2] Towards a continuous crystal APD-based PET detector design [J].

Bruyndonckx, Peter ;

Lemaitre, Cedric ;

Schaart, Dennis ;

Maas, Marnix ;

van der Laan, D. J. ;

Krieguer, Magalie ;

Devroede, Olivier ;

Tavernier, Stefaan .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2007, 571 (1-2) :182-186

[3]

CABELLO J, 2012, IEEE NUCL SCI S, pM16

[4]

Gillam JE, 2011, IEEE NUCL SCI CONF R, P4206, DOI 10.1109/NSSMIC.2011.6153806

[5] cMiCE: a high resolution animal PET using continuous LSO with a statistics based positioning scheme [J].

Joung, J ;

Miyaoka, RS ;

Lewellen, TK .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2002, 489 (1-3) :584-598

[6] Depth of γ-ray interaction within continuous crystals from the width of its scintillation light-distribution [J].

Lerche, CW ;

Benlloch, JM ;

Sánchez, F ;

Pavón, N ;

Escat, B ;

Gimenez, EN ;

Fernández, M ;

Torres, I ;

Giménez, M ;

Sebastià, A ;

Martínez, J .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2005, 52 (03) :560-572

[7] Nonlinear least-squares modeling of 3D interaction position in a monolithic scintillator block [J].

Li, Zhi ;

Wedrowski, M. ;

Bruyndonckx, P. ;

Vandersteen, G. .

PHYSICS IN MEDICINE AND BIOLOGY, 2010, 55 (21) :6515-6532

[8] Characterization of a PET detector head based on continuous LYSO crystals and monolithic, 64-pixel silicon photomultiplier matrices [J].

Llosa, G. ;

Barrio, J. ;

Lacasta, C. ;

Bisogni, M. G. ;

Del Guerra, A. ;

Marcatili, S. ;

Barrillon, P. ;

Bondil-Blin, S. ;

de la Taille, C. ;

Piemonte, C. .

PHYSICS IN MEDICINE AND BIOLOGY, 2010, 55 (23) :7299-7315

[9] A practical method for depth of interaction determination in monolithic scintillator PET detectors [J].

van Dam, Herman T. ;

Seifert, Stefan ;

Vinke, Ruud ;

Dendooven, Peter ;

Lohner, Herbert ;

Beekman, Freek J. ;

Schaart, Dennis R. .

PHYSICS IN MEDICINE AND BIOLOGY, 2011, 56 (13) :4135-4145

← 1 →