Hypothermic Circulatory Arrest Using Antegrade Cerebral Perfusion Is Safe for Elective Aortic Arch Surgery

被引:3
作者
Matt, Peter [1 ]
Albrecht, Franziska [1 ]
Rueter, Florian [1 ]
Grapow, Martin [1 ]
Pargger, Hans [2 ]
Fassl, Jens [2 ]
Reuthebuch, Oliver [1 ]
Eckstein, Friedrich [1 ]
机构
[1] Univ Basel Hosp, Div Cardiac Surg, CH-4031 Basel, Switzerland
[2] Univ Basel Hosp, Dept Anesthesia & Intens Care Med, CH-4031 Basel, Switzerland
关键词
aneurysm; aorta; aortic; outcomes; REPLACEMENT; PROTECTION; RETROGRADE;
D O I
10.1055/s-0032-1331466
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background We hypothesized that hypothermic circulatory arrest (HCA) can be performed with a low operative risk and does not add to the morbidity in elective procedures. Methods A total of 178 patients with a mean ( SD) age of 62 ( 10) years underwent HCA for elective aortic surgery from April 2008 to September 2011. Pre- and postoperative clinical data were collected prospectively. Results Hemiarch replacement was performed in 97% patients. Mean logistic Euroscore I was 17% (+/- 15). HCA was performed at 26 degrees C bilateral tympanic temperature. Mean HCA duration was 17 (+/-) min. Mean cross-clamp time was 106 (+/- 39) min. Overall 30-day mortality was 2% and stroke occurred in 4% of patients. Overall 6-month survival was 96%. Cox regression analysis for 6-month survival revealed four variables with significant influence: the logistic Euroscore I (p = 0.008), age (p = 0.04), cross-clamp time (p = 0.008), and reoperation for bleeding complications (p = 0.04). Conclusions HCA with open distal anastomosis for elective aortic repair can be performed with low operative mortality, even in the elderly, and seems not to add to the morbidity of the procedure.
引用
收藏
页码:553 / 558
页数:6
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