Photothermally Activated Hybrid Films for Quantitative Confined Release of Chemical Species

被引:28
作者
Matteini, Paolo [1 ]
Tatini, Francesca [1 ]
Luconi, Lapo [2 ]
Ratto, Fulvio [1 ]
Rossi, Francesca [1 ]
Giambastiani, Giuliano [2 ]
Pini, Roberto [1 ]
机构
[1] CNR, Inst Appl Phys Nello Carrara, I-50019 Carrara, Italy
[2] CNR, Inst Chem Organometall Cpds, I-50019 Rome, Italy
关键词
gold nanorods; light-sensitive materials; micelles; nanophotonics; photothermal conversion; GOLD NANORODS; POLYMERIC MICELLES; NANOPARTICLES; NANOSHELLS; HYDROGELS;
D O I
10.1002/anie.201207986
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Illuminating films of a porous chitosan matrix containing gold nanorods and thermosensitive micelles loaded with a chemical stimulates local photothermal conversion of the gold nanorods. The heat produced activates the ejection of the chemical from the micelles (see scheme), and causes the transient permeabilization of adjacent cell membranes, resulting in a selective cellular uptake of the released chemical with control over spatiotemporal parameters and dosage. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:5956 / 5960
页数:5
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