Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial

被引：15

作者：

Still, Carolyn H. ^{[1
,2
]}

Craven, Timothy E. ^{[3
]}

Freedman, Barry I. ^{[4
]}

Van Buren, Peter N. ^{[5
]}

Sink, Kaycee M. ^{[6
]}

Killeen, Anthony A. ^{[7
]}

Bates, Jeffrey T. ^{[8
,9
]}

Bee, Alberta ^{[1
]}

Contreras, Gabriel ^{[10
]}

Oparil, Suzanne ^{[11
]}

Pedley, Carolyn M. ^{[12
]}

Wall, Barry M. ^{[13
]}

White, Suzanne ^{[14
]}

Woods, Delia M. ^{[15
]}

Rodriguez, Carlos J. ^{[16
]}

Wright, Jackson T., Jr. ^{[1
,17
]}

机构：

[1] Univ Hosp Case Med Ctr, Clin Hypertens Program, Div Nephrol & Hypertens, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Cleveland, OH 44106 USA

[3] Wake Forest Sch Med, Dept Biostat, Winston Salem, NC USA

[4] Wake Forest Sch Med, Nephrol Sect, Dept Internal Med, Winston Salem, NC USA

[5] Univ Texas SW Med Ctr Dallas, Dept Internal Med, Div Nephrol, Dallas, TX 75390 USA

[6] Wake Forest Sch Med, Sect Geriatr & Gerontol, Winston Salem, NC USA

[7] Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA

[8] Michael E DeBakey VA Med Ctr, Houston, TX USA

[9] Baylor Coll Med, Houston, TX 77030 USA

[10] Univ Miami, Miller Sch Med, Dept Nephrol, Miami, FL 33136 USA

[11] Univ Alabama Birmingham, Dept Med, Div Cardiovasc Dis, Birmingham, AL 35294 USA

[12] Wake Forest Baptist Hlth, Wake Forest Sch Med, Dept Internal Med, Winston Salem, NC USA

[13] Memphis Vet Affairs Med Ctr, Memphis, TN USA

[14] Northeast Ohio Neighborhood Hlth Serv Inc, Dept Internal Med, Cleveland, OH USA

[15] Vanderbilt Univ, Dept Med, Div Nephrol, Nashville, TN USA

[16] Wake Forest Sch Med, Sect Cardiovasc Med, Dept Epidemiol & Prevent, Winston Salem, NC USA

[17] Case Western Reserve Univ, Sch Med, Dept Hypertens & Nephrol, Cleveland, OH USA

来源：

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION | 2015年 / 9卷 / 09期

基金：

美国国家卫生研究院;

关键词：

Cardiovascular disease; blacks; clinical trials; hypertension; SPRINT; INTERNATIONAL-SOCIETY; PULSE PRESSURE; OLDER-ADULTS; HYPERTENSION; MANAGEMENT; DISEASE; RISK; ASSOCIATION; AMLODIPINE; GUIDELINES;

D O I：

10.1016/j.jash.2015.06.012

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The Systolic Blood Pressure Intervention Trial (SPRINT) will compare treatment to a systolic blood pressure goal of <120 mm Hg to treatment to the currently recommended goal of <140 mm Hg for effects on incident cardiovascular, renal, and neurologic outcomes including cognitive decline. The objectives of this analysis are to compare baseline characteristics of African American (AA) and non-AA SPRINT participants and explore factors associated with uncontrolled blood pressure (BP) by race. SPRINT enrolled 9361 hypertensive participants aged older than 50 years. This cross-sectional analysis examines sociodemographics, baseline characteristics, and study measures among AAs compared with non-AAs. AAs made up 31% of participants. AAs (compared with non-AAs) were younger and less frequently male, had less education, and were more likely uninsured or covered by Medicaid. In addition, AAs scored lower on the cognitive screening test when compared with non-AAs. Multivariate logistic regression analysis found BP control rates to <140/90 mm Hg were higher for AAs who were male, had higher number of chronic diseases, were on diuretic treatment, and had better medication adherence. SPRINT is well poised to examine the effects of systolic blood pressure targets on clinical outcomes as well as predictors influencing BP control in AAs. (C) 2015 American Society of Hypertension. All rights reserved.

引用

页码：670 / 679

页数：10

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